Ribozyme Pharmaceuticals, Incorporated

Sirna Therapeutics, Inc.

Amber Beaudry

Leonid Beigelman

Jasenka Matulic-Adamic

Alexander Karpeisky

David Sweedler

Alex B Burgin

Shawn Patrick Zinnen

Novel nucleotide triphosphates, methods of synthesis and process of incorporating these nucleotide triphosphates into oligonucleotides, and isolation of novel nucleic acid catalysts (e.g., ribozymes) are disclosed. Also, described are the use of novel enzymatic nucleic acid molecules to inhibit HER2/neu/ErbB2 gene expression and their applications in human therapy.

Oligoribonucleotides with enzymatic activity

Synthetic ribonucleic acids with RNAse activity

Novel nucleoside triphosphates, methods of synthesis and process of incorporating these nucleoside triphosphates into oligonucleotides are disclosed.

Nucleoside triphosphates and their incorporation into oligonucleotides

Novel nucleotide triphosphates, methods of synthesis and process of incorporating these nucleotide triphosphates into oligonucleotides, and isolation of novel nucleic acid catalysts (e.g., ribozymes) are disclosed.

Growing community of inventors

Broomfield, CO, United States of America

Amber Beaudry