Other

University of Delhi, Department of Chemistry

Registrar, University of Delhi

Amarnath Maitra

Sanjeeb Kumar Sahoo

Rama Mukherjee

Anand C Burman

Dhiraj Khattar

Prasanta Kumar Ghosh

Sumit Madan

Mukesh Kumar

Ajay Kumar Gupta

Dipak Majumdar

Susmita Mitra

Subho Mozumdar

Indrajit Roy

Soumendu Paul

Tapas K De

Prashant Kumar Ghosh

The present invention relates to sustained release and long residing opthalmic formulation having thermosensitivity, mucoadhesiveness, hydro gel properties and small particle size. The said formulation comprises micelle solution of random block co-polymer having a hydrophobic component and a hydrophillic component of general formula &mdash;(X&plus;Y&plus;Z-) , and at least one hydrophobic drug with the block co-polymer solution. The invention also provides a process of preparing said formulation.

Sustained release and long residing ophthalmic formulation and the process of preparing the same

The present invention relates to a process of entrapping genetic materials in nanoparticles of inorganic metal salts of size below 100 nm diameter to form non-viral carriers for delivery of genes. The process comprises the steps of dissolving surfactants and a cosurfactant in oil to obtain reverse micelles. An aqueous solution of genetic material is added to the reverse micelles. Thereafter the reverse micelles are divided into two equal parts. To one part, aqueous solution of inorganic metal salts is dissolved to obtain optically clear and transparent reverse micelles. To the second part aqueous solution of precipitating agent is added to obtain optically clear and transparent reverse micelles. The two equally divided parts of reverse micelles are mixed to form inorganic nanopartcles encapsulating added genetic material. Thereafter, the nanoparticles are separated from reverse micelles, the inorganic nanoparticles are dispersed in water and dialyzed to remove free metal salts, surfactant and oil.

Process of entrapping genetic materials in ultra-low size nanoparticles of inorganic compounds to form non-viral carriers

This invention relates to pharmaceutical formulations of paclitaxel, its derivatives or analogs entrapped into nanoparticles of co-polymeric micelles, a process for preparing the same and the use thereof.

Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof

Preparation of highly monodispersed polymeric hydrophilic nanoparticles having a size of up to 100 nm (in which may have drug substances encapsulated therein. The process comprises subjecting a mixture of an aqueous solution of a monomer or preformed polymer reverse micelles, a cross linking agent, initiator, and optionally, a drug or target substance to polymerization. The polymerized reaction product is dried for removal of solvent to obtain dried nanoparticles and surfactant employed in the process of preparing reverse micelles. The dry mass is dispersed in aqueous buffer and the surfactant and other toxic material are removed therefrom.

Process for the preparation of highly monodispersed polymeric

Growing community of inventors

Delhi, India

Amarnath Maitra