Indian Institute of Technology, Guwahati

Amaresh Kumar Sahoo

Arun Chattopadhyay

Anumita Paul

Sunil Kumar Sailapu

Deepanjalee Dutta

Srestha Basu

Siddhartha Sankar Ghosh

The present invention discloses a diagnostic device or kit for visual detection of bilirubin. Said diagnostic device or kit comprises chitosan stabilized gold nanoclusters based luminescence source, Cuions source for quenching luminescence intensity of said gold nanoclusters and recovery of quenched luminescence intensity in the presence of bilirubin. The said device enables non-invasive detection of hyper-bilirubinemia by thumb impression visually or from blood serum.

Device for visual detection of bilirubin

A device with integrated methods for carrying out reverse transcription polymerase chain reaction (RT-PCR) and/or array based analysis involving signal generating agents (gold nanoclusters) comprising a heating and cooling cycle based synthesis selectively with DIMA and protein as templates. The advancement is further directed to a portable device adapted for RT-PCR and array based gene and protein expression analyses based on a common detection agent involving luminescence of in-situ synthesized gold nanoclusters with adaptability for user friendly graphical user interface (GUI) for controlling, visualization and analysis of the data.

Device with integrated methods for reverse transcription polymerase chain reaction (RT-PCR) and/or DNA/protein array based analyses

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Assam, India

Amaresh Kumar Sahoo