Sysmex Corporation

Kyushu University

Kobe University

Amane Harada

Keiko Yoshikawa

Ryuji Toh

Keiko Miwa

Maria Kiriyama

Katsuhiro Murakami

Takuya Kubo

Tomokazu Yoshida

Yoichiro Hirakawa

Toshiharu Ninomiya

Yasuhiro Irino

The present invention relates to a method for measuring the cholesterol uptake capacity of lipoproteins. The present invention also relates to a reagent kit for measuring the cholesterol uptake capacity of lipoproteins. The present invention further relates to a tagged cholesterol which can be used in the method and the reagent kit.

Method for measuring cholesterol uptake capacity of lipoproteins

Provided is a method of measuring a lipoprotein's capacity to accept cholesterol including the steps of bringing a lipoprotein in a sample into contact with labeled cholesterol to incorporate the labeled cholesterol into the lipoprotein, bringing the lipoprotein having the labeled cholesterol into contact with an antibody that binds to a lipoprotein to form a complex of the lipoprotein and the antibody, and measuring the label incorporated into the complex.

Method of measuring lipoprotein's capacity to accept cholesterol

The present invention provides a method for determining susceptibility to an anthracycline anticancer agent, comprising the steps consisting of detecting the expression of activated Akt in a cancer cell or cancer tissue and determining the susceptibility of the cancer cell or cancer tissue to the anthracycline anticancer agent on the basis of the detection result. The method for determining the susceptibility to an anticancer agent can be used in objective and accurate determination of the susceptibility of a cancer cell or cancer tissue to an anthracycline anticancer agent without imposing a heavy burden on a patient.

Method for determining the efficacy of an anthracycline anticancer agent

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Kobe, Japan

Amane Harada