Sun Pharmaceutical Industries Limited

Concert Pharmaceuticals, Inc.

Amanda T Wagner

Jana Von Hehn

Colleen E Hamilton

Virginia Braman

Vinita Uttamsingh

Philip B Graham

James Cassella

James V Cassella

Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an amount in the range of about 4 mg to about 50 mg of Compound (I): or a pharmaceutically acceptable salt thereof. This invention also provides compositions comprising Compound (I) and the use of such compositions in the described methods.

Treatment of hair loss disorders with deuterated JAK inhibitors

Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an amount in the range of about 4 mg to about 50 mg of Compound (I), or a pharmaceutically acceptable salt thereof. This invention also provides compositions comprising Compound (I) and the use of such compositions in the described methods. 

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Watertown, MA, United States of America

Amanda T Wagner