Southern Research Institute

Amanda McRae-McFarlane

Thomas R Tice

David W Mason

Deborah L Dillon

Annica B Dahlstrom

Annica Dahlstromm

The present invention relates to polymeric microspheres as injectable, drug-delivery vehicles for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient. Microspheres of less than 45 &mgr;m, preferably less than about 20 &mgr;m, and preferably about 0.1 &mgr;m to about 10 &mgr;m in mean diameter according to the present invention are also selectively taken-up and into astrocytes when delivered directly into the nervous tissues.

Microcapsules for administration of neuroactive agents

The present invention relates to polymeric microspheres as injectable, drug-delivery systems for use to deliver bioactive agents to sites within the central nervous system, and for the stimulation of nerve fiber growth by implanting such microspheres within the central nervous system of a patient.

Growing community of inventors

Birmingham, AL, United States of America

Amanda McRae-McFarlane