Bruker Cellular Analysic, Inc.

Bruker Cellular Analysis, Inc.

Amanda L Goodsell

Alexander J Mastroianni

Kevin T Chapman

Peter J Beemiller

Natalie C Marks

Yelena Bronevetsky

Guido K Stadler

Hansohl E Kim

Thomas M Vetterli

Vincent Haw Tien Pai

Annamaria Mocciaro

Jason M Mcewen

John A Tenney

Duane Smith

Jr Randall D Lowe

Andrew W Mcfarland

Methods are provided for the assay of secreted biomolecules using automated detection and characterization of micro-objects in a microfluidic device. The biomolecules can be secreted by cells, particularly immunological cells, such as T cells. The biomolecules being assayed can include cytokines, growth factors, and the like. Methods are also provided for assaying the cytotoxicity of a cell with respect to another, target cell. Also provided are kits and non-transitory computer-readable media in which programs are stored for causing a system comprising a computer to perform automated methods for detecting secreted biomolecules and/or cytotoxicity in a microfluidic device.

Methods for assaying biological cells in a microfluidic device

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Emeryville, CA, United States of America

Amanda L Goodsell