University of Leeds

Amalia Aggeli

Eileen Ingham

Neville Boden

Jennifer Kirkham

Ruth Karen Wilcox

Danielle Elizabeth Miles

There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a &#x3b2;-sheet tape-like substructure.

Beta sheet tapes ribbons in tissue engineering

Novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefore are described. The novel self-assembling peptide complexes have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues. Methods of repairing and or restoring biomechanical or biochemical function of biological tissues and scaffolds for the support of cell growth are also described.

Self-assembling peptide and polysaccharide complexes

There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a &#x3b2;-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.

&#x3b2;sheet tapes ribbons in tissue engineering

There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a &#x3b2;-sheet tape-like substructure.

Growing community of inventors

Thessaloniki, Greece

Amalia Aggeli