Commissariat a L'energie Atomique Et Aux Energies Alternatives

Perha Pharmaceuticals

Women & Infants Hospital of Rhode Island

Scientiam Pharma

Aloïse Mabondzo

Sophie Dezard

Henri Benech

Gabriela Ullio-Gamboa

Frédéric Taran

Olivier Loreau

Laurent Meijer

Nassima Oumata

Frederic Taran

Hervé Galons

Anne-Cécile Guyot

Alexandra Trotier-Faurion

Charlotte Leuxe

Narciso Costa

Alain Pruvost

Clémence Disdier

A composition comprising at least one creatine fatty ester or salt thereof, at least one omega 3 fatty acid or salt thereof and at least one glyceride for use in medicine, the composition being free of non ionic surfactants and in particular said composition for use in treating the brain creatine transporter deficiency disease.

Composition containing creatine fatty ester for use in medicine

A composition in the form of a micro-emulsion composed of an oil phase comprising at least one omega 3 fatty acid or salt thereof and at least one glyceride, an aqueous phase and one or more non ionic surfactant(s), said composition containing at least one creatine fatty ester or salt thereof. Further, a method for preparing such a composition and its use in medicine in particular for treating the brain creatine transporter deficiency disease.

Micro-emulsion containing creatine fatty-ester, method for preparing said micro-emulsion and uses thereof

Compound of formula (I) and its addition salts with pharmaceutically acceptable acids, and methods in which an effective amount of the compound or any pharmaceutically acceptable salt thereof is administered (as a medicament) to an individual in need thereof.

Purine derivatives for use as medicament and for use in treating neurodegenerative or neuro-inflammatory disorders

The present invention concerns a method for preparing a creatine fatty ester or derivative thereof comprising at least one step consisting in reacting a diprotected creatinine with a molecule bearing at least one alcohol functional group and of formula R'&#x2014;OH in which R&#x2032; represents a hydrocarbon radical containing at least 4 carbon atoms. The present invention also concerns particular creatine fatty esters or derivative thereof and medical uses thereof.

Method for preparing creatine fatty esters, creatine fatty esters thus prepared and uses thereof

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Paris, France

Aloïse Mabondzo