Versitech, Inc.

British Columbia Cancer Agency Branch

Bagi Research Limited

Allan Sik-Yin Lau

Steven J Jones

Lit Man Poon

Lai Hung Cindy Yang

Stanley Chi Chung Chik

Jianghong An

Anna Hing-Yee Law

Cindy Lai Hung Yang

Hing-Yee Law

Chun-Wai Davy Lee

Hing Yee Law

Chun Wai Davy Lee

Stanley Chi Chik

Cindy Lai Yang

Carbamimidothioic acid esters of formula (I) and 2-nitro-N-[4-(pyridin-4-ylamino)phenyl]-4-(quinolin-4-ylamino)benzamide are used for the treatment of influenza, and for the inhibition of a viral RNA-dependent RNA polymerase. Formulae (I), (II).

Anti-viral carbamimidothioic acid esters

The present invention provides pyrimidinyl compounds of formula (I) and pharmaceutically acceptable salts thereof. These compounds may be used for the inhibition of influenza. In particular, the compounds of the invention may be used for the treatment or prophylaxis of influenza A, most particularly H1N1 or H5N1 influenza. The compounds of the invention can also be used for the treatment or prophylaxis of a disease caused by, an orthomyxovirus, a paramyxovirus, a parainfluenza virus, mumps virus, Newcastle disease virus, fowl plague virus or Sendai virus. 

Anti-influenza compounds

Growing community of inventors

Hong Kong, China

Allan Sik-Yin Lau