Tel Aviv University

Alissa Naugolny

Ido M Herzog

Micha Fridman

Yoram Cohen

Roymon Joseph

Dana Kaizerman

Mark Feldman

Cationic pillar[n]arenes, e.g., positively charged poly-ammonium, poly-phosphonium and poly-imidazolium pillar[5-6]arene derivatives are capable of inhibiting or preventing biofilm formation, and facilitating existing biofilm decomposition. A composition for inhibiting or disrupting biofilm, e.g., bacterial or fungal biofilm, formation, or reducing biofilm, can include a pharmaceutically acceptable carrier, and a cationic pillar[n]ene.

Method for inhibiting or disrupting biofilm formation, or reducing biofilm

The present invention provides cationic pillar[n]arenes, e.g., positively charged poly-ammonium, poly-phosphonium and poly-imidazolium pillar[5-6]arene derivatives, capable of inhibiting or preventing biofilm formation, and facilitating existing biofilm decomposition; as well as compositions thereof and methods of use.

Cationic pillararenes and uses thereof

Growing community of inventors

Tel Aviv, Israel

Alissa Naugolny