Akzo Nobel N.v.

Akzo N.v.

Alison A Fleming

James F Gadberry

Robert F Farmer

Meiylin F Antezzo

An .alpha.-aminonitrile compound derived from the reaction, in the presence of a cyanide source of (1) a bisulfite adduct of a carbonyl compound selected from the group consisting of an aldehyde and a ketone with (2) a fatty alkyl alkylene diamine containing two reactible amino functionalities which is of the formula RNHR.sub.1 NH.sub.2, where R is fatty alkyl and R.sub.1 is lower alkylene of up to six carbon atoms.

.alpha.aminonitriles derived from reaction of carbonyl compounds and

.alpha.-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed which are of the formula ##STR1## where R is C.sub.12 -C.sub.22 fatty alkyl, R.sub.1 is alkylene, R.sub.2 is alkyl, and R.sub.3 is alkyl or hydrogen.

.alpha.-aminodinitriles containing fatty alkyl C.sub.12 to C.sub.22 group

.alpha.-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed which are of the formula ##STR1## where R is C.sub.12 -C.sub.22 fatty alkyl, R.sub.1 is alkylene, R.sub.2 is aryl, and R.sub.3 is alkyl, aryl, or hydrogen.

.alpha.-aminomononitriles containing fatty alkyl C.sub.12 to C.sub.22

.alpha.-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed which are of the formula ##STR1## where R is C.sub.12 -C.sub.22 fatty alkyl, R.sub.1 is alkylene, R.sub.2 is aryl, and R.sub.3 is aryl or hydrogen.

.alpha.-aminonitrile compounds can be synthesized by reacting a carbonyl compound, for example an aldehyde, such as, one containing an alkyl group, with a fatty amine hydrohalide, for example, a fatty amine hydrochloride, in the presence of a cyanide source, for example, an alkali metal cyanide.

Process for forming .alpha.-aminonitriles from carbonyl compound and

.alpha.-aminonitrile compounds derived from a fatty alkyl alkylene diamine containing two reactible amino functionalities are disclosed.

.alpha.-aminonitriles derived from fatty alkyl alkylene diamines

The bisulfite adduct of a carbonyl compound, amine, and alkali metal cyanide are reacted in aqueous media to form an organic layer containing the desired .alpha.-aminonitrile product and an aqueous layer containing alkali metal sulfite. The aqueous layer, after separation from the organic layer, can be used as the reaction medium in a fresh reaction of bisulfite adduct, amine and alkali metal cyanide after its pH has been adjusted to the moderately acidic range, e.g., a pH of about 4 to about 5.

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Mohegan Lake, NY, United States of America

Alison A Fleming