Centre National De La Recherche Scientifique

Universitéde Strasbourg

Hong Kong Baptist University

Université Paris-saclay

Commissariat a L'energie Atomique

Université Paris—sud

Aline Nonat

Marinella Mazzanti

Loïc Charbonniere

Niko Hildebrandt

Ka-Leung Wong

Vjona Cifliku

Cyrille Charpentier

Joan Goetz

Christelle Gateau

Marcelina Cardoso Dos Santos

The invention provides luminescent lanthanide nanoparticles having simultaneously an improved brightness and an increased lifetime of the excited-state. These nanoparticles comprise terbium ions and ions of a second lanthanide, preferentially europium, and are coated with molecules of chromophore ligand bonded to the surface of the nanoparticle. The ligand is an organic molecule comprising at least one chromophore radical of formula (I) or of formula (II): wherein R is selected from H, CN group or COOH group. The phosphorescence excited-state lifetime is improved by energy transfer from surface terbium ions to core ions of the second lanthanide. The nanoparticle may further comprise a carrier molecule of analytical interest covalently attached to at least one ligand molecule.

Ultrabright luminescent lanthanide nanoparticles comprising terbium, with longer excited-state lifetime

Growing community of inventors

Eckbolsheim, France

Aline Nonat