Multiply Labs Inc.

Alice Melocchi

Federico Parietti

Lawrence Zachary Bright

Kameron C Chan

Jeffrey Curhan

Roger Lo

Michelle Chen

Umberto Scarfogliero

Nolan Dickey

Joaquin Giraldo-Laguna

Sam Ihns

Lucia Zema

Andrea Gazzaniga

Jeffrey Ackerman Cuhran

A docking device for receiving a portable device. The docking device includes a base including a substantially planar upper surface for supporting a portable device. The docking device includes an array of a plurality of engagement members. Each engagement member in the plurality of engagement members includes a fixed body protruding upwardly from the substantially planar upper surface of the base. Each engagement member includes a spring including a fixed end portion and a free end portion for engagement with the portable device. The fixed end portion interfaces with the fixed body. The free end portion protrudes from the fixed end portion obliquely towards the substantially planar upper surface of the base. The free end being movable along a deformable gap between a first surface of the fixed body and a second surface of the spring.

System, method, and apparatus facilitating automated modular manufacture of cell therapy

A rigid cartridge for housing and removably coupling with a soft body bioreactor is provided. The rigid cartridge includes rigid walls defining a rigid housing. The rigid walls expose a fixed interior configured to house the soft body. An interior surface of a first rigid wall includes a first mating mechanism to engage a second mating mechanism of the soft body to removably coupled with the rigid cartridge and accommodate the soft body in the fixed interior of the rigid cartridge. A rigid wall includes a planar upper surface including an aperture. Each aperture is encompassed by an annular hood protruding upwardly from the substantially planar upper surface and integrally formed with the at least one rigid wall. The aperture is configured to receive and fixed engage a corresponding connector. Each connector includes a rigid coupling mechanism that provides communication with a corresponding plurality of ports of the soft body.

An automated batch filling apparatus comprising a first base comprising a first plurality of metering holes, a trough slidably disposed on an upper surface of the first base, one or more guides configured to constrain a motion of the trough, a gate disposed on a bottom surface of the first base, wherein the gate comprises a second plurality of metering holes, a second base disposed below the gate, wherein the second base comprise a third plurality of metering hole, and one or more vibration devices, wherein the one or more vibration devices are configured to agitate the filling apparatus.

Automated batch filling apparatus

A method of making a capsule comprising a plurality of compartments, the method comprising: initiating extrusion of a filament solution through a filament extruder; laying the filament solution to form a base of the capsule; forming a first compartment in the plurality of compartments, wherein the forming creates a first barrier wall having a first predetermined release time; forming a second compartment in the plurality of compartments, wherein the forming creates a second barrier wall having a second predetermined release time; filling the first compartment with a first material; filling the second compartment with a second material; and sealing the plurality of compartments thereby forming the capsule with a first sealed compartment and a second sealed compartment.

Multi-compartment capsule

A dispensing system comprises a main base with a hopper insertion hole. An upper base, fixed above the main base by spacers, comprises a stirrer insertion hole. A lower base, below the main base, has a hopper insertion hole with an aperture larger than a diameter of a hopper, and is coupled to the main base by a guide. A rotatable hopper, disposed in the insertion hole of the main base, comprises a bottom surface with metering holes. A stirrer, inside the hopper and fixed to the upper base, feeds material into the metering holes. A gate, on a bottom surface of the lower base, comprises a bottom surface with a dispensing hole. The gate diameter is greater than the hopper. A gate spring, between the bottom of the main base and an upper surface of the lower base, is mounted parallel to a sliding motion of the lower base. A vibration device agitates the assembly on the main base.

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Dalmine, Italy

Alice Melocchi