European Community

Institut National De La Sante Et De La Recherche Medicale

Ali Ouadi

Christos Apostolidis

Jean-François Gestin

Jean-Francois Gestin

The invention concerns a ligand comprising wherein n is an integer from 1 to 5, X represents &#x2014;NO, &#x2014;NH, &#x2014;NCS, &#x2014;NHCOCH-Z. NHCO&#x2014;W&#x2014;COCNHS, &#x2014;NH-Q, &#x2014;NHCS-Q, &#x2014;NHCOCH-Q, or &#x2014;NHCO(CH)m ?-Q where Q is an hapten chosen from the group consisting of steroids, enzymes, proteins, monoclonal antibodies, chimeric antibodies, or fragments thereof or any activated linker ready for coupling reaction, Y is COH or POHW is &#x2014;(CH)&#x2014; m is an integer from 1 to 10. Z is chloride, bromide or iodine 

Bifunctional chelating agent

The invention concerns a ligand comprising (I) wherein n is an integer from 1 to 5 Y is CO2H or PO3H2T represents &#x2014;X or -phenyl-X, wherein X represents NO2, NH2, NCS, NHCOCH2-Z, NHCO&#x2014;W&#x2014;COCNHS, &#x2014;NH-Q, &#x2014;NHCS-Q, &#x2014;NHCOCH2-Q, or NHCO(CH2)m-Q where Q is a hapten chosen from the group consisting of steroids, enzymes, proteins, monoclonal antibodies, chimeric antibodies, or fragments thereof or any activated linker ready for coupling reaction, W is &#x2014;(CH2)m- m is an integer from 1 to 10 Z is chloride, bromide or iodine 

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Eggenstein, Germany

Ali Ouadi