Akonni Biosystems, Inc.

Keck Graduate Institute

Other

Claremont Biosolutions LLC

Keck Graduate Insitute

Ali Nadim

Anna Hickerson

James D Sterling

Christopher G Cooney

Bruce D Irvine

Robert Doebler

Reza Miraghaie

Robert W Doebler, Ii

Phil Belgrader

Ryan P Talbot

Barbara Erwin

Denice Woyski

Phillip Belgrader

Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.

System, apparatus and method for material preparation and/or handling

An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.

Systems and devices for isothermal biochemical reactions and/or analysis

A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.

Temperature control device with a flexible temperature control surface

Growing community of inventors

San Marino, CA, United States of America

Ali Nadim