Nuvasive, Inc.

Ali Ismailoglu

Susan Riley

Gregory Williams

Timothy Moseley

Erik Erbe

Sung-Ching Chen

Kehsin Chien

Po-Hung Lai

Frank Vizesi

A bone graft composition comprising a viable, osteogenic cellular material combined with a viscous cryoprotectant that includes a penetrating cryoprotective agent and a non-penetrating cryoprotective agent. The viscosity of the cryoprotectant is such that the composition is malleable, cohesive and capable of being formed into desired shapes.

Malleable, cryopreserved osteogenic compositions with viable cells

An osteoinductive bone graft substitute including an osteoinductive calcium phosphate component retained within a collagen scaffold, wherein the collagen scaffold is formulated to maintain the osteoinductivity of the calcium phosphate component while also exhibiting the following characteristics (1) ability to absorb bone marrow and/or other physiologic liquids, (2) compression resistance; (3) moldability; (4) retaining the calcium phosphate component during and after manipulation of the collagen scaffold and (5) fibrous collagen matrix that retains but does not occlude the osteoinductive calcium phosphate component.

Osteoinductive bone graft substitute

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San Diego, CA, United States of America

Ali Ismailoglu