Synergeyes, Inc.

Ali Dahi

Jerome A Legerton

Barry Chen

Joe H Collins

Ramezan Benrashid

Ramazan Benrashid

William E Meyers

Hermann H Neidlinger

Joseph Collins

Jenny Xuan Huynh

A hybrid contact lens includes a substantially rigid center portion and a substantially flexible skirt portion connected to the center portion. The skirt portion is formed using xerogels compatible with diluents comprising at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide. These diluents are formulated to function as a stand-in for water in the xerogel polymer, allowing the xerogel to form and bond to the rigid center portion in its fully expanded state. Upon hydration of the hybrid lens, substantially little dimensional change, and thus substantially little distortion, is obtained in the skirt portion. The diluents of the present invention further preserve the mechanical integrity of the xerogel, allowing the xerogel to be machined to final shape, improving the dimensional tolerances which can be achieved in the hybrid lens.

Hybrid contact lenses prepared with expansion controlled polymeric materials

A hybrid contact lens comprises a central zone comprising a substantially rigid, gas permeable material having a DK of at least 30, a relatively soft peripheral zone and an intermediate zone comprising a film or coating that is created around the central zone, and then cured. The film facilitates chemical bonding between the central zone and the peripheral zone, and also provides a protective barrier to prevent modification of the physical characteristics of the central zone. The film may be created by soaking the central zone in a chemical solution for a predetermined amount of soaking time.

Hybrid contact lens system and method

The present invention relates to contact lenses manufactured using a gas permeable material with improved hydrophilicity. A method for improving the hydrophilicity of the contact lens includes providing a contact lens comprising a gas permeable contact lens material and exposing the material to a treatment solution comprising a chemical agent under conditions that are effective to significantly reduce the contact angle of the contact lens for a period of at least about two months. In another embodiment, the method includes irradiating the contact lens to sterilize the contact lens material. A contact lens manufactured using this method includes a substantially rigid portion comprising a polymeric material, the polymeric material comprising a hydrophilic surface having a contact angle of about 65 degrees or less.

Methods for improving the hydrophilicity of contact lenses and contact lenses having the same

Methods of manufacturing hybrid contact lenses using a mold are provided. The methods include pouring liquefied resin of a substantially rigid material within an inner section, curing the substantially rigid material, pouring liquefied resin of a substantially flexible material within an outer section and curing the substantially flexible material. In some embodiments, a wall disposed between the rigid and flexible materials is angled and/or bent to increase bonding strength between the rigid and flexible sections. The curing steps involve the application of heat, UV light, or a combination of both heat and UV light.

A hybrid hard-soft contact lens is provided. Several embodiments of the invention include methods of coupling the hard and soft sections of the contact lens. Other embodiments of the invention include contact lens materials and coatings that increase oxygen transmission though the lens. Yet other embodiments of the invention are directed to cost-effective manufacturing methods of a hybrid hard-soft contact lens. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims.

A method of manufacturing a hybrid contact lens having a substantially rigid center portion and a substantially flexible outer portion, comprising forming the substantially rigid center portion, treating the substantially rigid center portion to form a coating on the perimeter of the substantially rigid portion, forming the substantially flexible outer portion around the substantially rigid center portion and chemically bonding the substantially flexible portion to the substantially rigid portion. Hybrid lenses comprising a substantially rigid center portion and a substantially flexible outer portion joined at junction comprising a first segment and a second segment are also provided.

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Carlsbad, CA, United States of America

Ali Dahi