King Saud University

Ali Ali El-Gamal

Shaza Mohamed Adel Al-Massarani

Rabab Abd El Moneim Khalil El Dib

Manal Ahmed Gasmelseed Awad

Adnan Jathlan Al-Rehaily

Manal Ahmed Gasmelseed

In one embodiment, synthesis ofnanoparticles includes providing apowder; dissolving the powder in a first alcohol to provide a first alcohol extract; concentrating a filtrate from the first alcohol extract under reduced pressure to provide a dried alcohol extract; dissolving the dried alcohol extract in the first alcohol to provide a second alcohol extract; successively partitioning the second alcohol extract using n-hexane to provide an n-hexane extract; dissolving the n-hexane extract in a second alcohol and water to provide a first solution; and adding an acidic solution to the first solution to form a final solution includingnanoparticles.

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A method for synthesizing 3-oxolupenal nanoparticles including isolating 3-oxolupenal from a fraction ofplant, reducing the 3-oxolupenal to obtain a powder of 3-oxolupenal, dissolving the powder of 3-oxolupenal in methanol to form a first solution, adding the first solution to boiling water to form a second solution, sonicating the second solution, and freeze-drying after sonication to obtain the synthesized 3-oxolupenal nanoparticles. The synthesized 3-oxolupenal nanoparticles exhibited cytotoxic effects and antimicrobial effects.

Method of synthesizing of 3-oxolupenal nanoparticles

Synthesis ofnanoparticles includes providing an extract of, dissolving the extract in alcohol to provide a mixture, adding water to the mixture to provide an aqueous solution, adding an acidic solution to the aqueous solution to form a final solution includingnanoparticles; and centrifuging the final solution to isolate thenanoparticles.

Synthesis of ifflaionic acid nanoparticles includes dissolving a powder of ifflaionic acid in an alcohol solution to form a first solution, adding the first solution to an aqueous solution under ultrasonic conditions to produce a sonicated solution, stirring the sonicated solution for a duration of time to produce a mixture, and freeze-drying the mixture to provide the ifflaionic acid nanoparticles.

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Riyadh, Saudi Arabia

Ali Ali El-Gamal