Smithkline Beckman Corporation

Alfred W Chow

Winfred J Sanders

Thomas O Lindsey

Vassilios J Theodorides

Selected pyridylalkylhydrazides are used as active ingredients in animal feed compositions and in methods for increasing the growth and feed efficiency of monogastric, meat-producing animals. A particularly useful active ingredient of this invention is 3-azabicyclo-[3.2.2]nonane-3-carbothioic acid 2-[1-(2-pyridyl)ethyl]-hydrazide.

Feed compositions containing pyridylalkylhydrazides

Flukicidal N-[4-(1-phenylethenyl)phenyl]-2-hydroxy-3,5-dihalobenzamides are prepared by reacting a halosalicylic acid with a 1-(4-aminophenyl)-1-phenylethylene in the presence of a halo condensing agent. A species of the invention is N-[4-(1-phenylethenyl)phenyl]-2-hydroxy-3,5-diiodobenzamide.

Anthelmintic benzamides

1-(3,4-bis-(3-lower alkoxycarbonyl)-2-thioureido)-phenyl)-1-phenylethylenes, which have anthelmintic activity, are prepared by reacting various 1-(3,4-diaminophenyl)-1-phenylethylenes with an alkoxycarbonylisothiocyanate which is prepared, in turn, from an alkali metal thiocyanate and a lower alkyl haloformate.

1-(3,4-Bis-(3-(lower

New 2-acylamino-5-phenylethenylbenzimidazoles have been prepared and found to have anthelmintic activity. A species of the invention is methyl [5-(1-phenylethenyl)-1H-benzimidazol-2-yl]carbamate.

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Radnor, PA, United States of America

Alfred W Chow