Sony Dadc Austria Ag

Sony Corporation

Harvard College

Stratec Consumables Gmb

Stratec Consumables Gmbh

Wen, Norman

Novak, Richard

Fernandez-alcon, Jose

Alfred Paris

Georg Bauer

Thomas Umundum

Donald Elliot Ingber

Daniel Levner

Christopher David Hinojosa

Gabriele Nelles

Norman Wen

Geraldine A Hamilton

Silvia Rosselli

Jose Fernandez-Alcon

Richard Novak

Nikolaus Knorr

Remi Villenave

Gerda Fuhrmann

Guy Thompson

Karel Domansky

Kambez Hajipouran Benam

Dario Borovic

Wolfgang Reiter

Thomas Buttinger

Maria Kaufmann

Michael Pingert

Daniel Horner

Michael Schmid

Ii Guy Thompson

An organomimetic device includes a microfluidic device that can be used to culture cells in its microfluidic channels. The organomimetic device can be part of dynamic system that can apply mechanical forces to the cells by modulating the microfluidic device and the flow of fluid through the microfluidic channels. The membrane in the organomimetic device can be modulated mechanically via pneumatic means and/or mechanical means. The organomimetic device can be manufactured by the fabrication of individual components separately, for example, as individual layers that can be subsequently laminated together.

Organomimetic devices and methods of use and manufacturing thereof

A microfluidic flow controller comprising a substrate having formations defining two or more fluid channels having channel fluid ports which are open at an outer surface of the substrate; and a flexible layer having formations defining a fluid channel which, when the flexible layer is positioned over the substrate so as to cover at least the channel fluid ports, provides a fluid communication path between the channel fluid ports but which, when a force is applied to press the flexible layer towards the substrate, deforms so as to inhibit fluid communication between the channel fluid ports.

Microfluidic flow control and device

The present invention relates to a polymeric substrate having a glass-like surface, in particular an etched-glass-like surface and to a chip made of at least one such polymeric substrate. The present invention also relates to a method of providing a polymeric substrate with an etched-glass-like surface. Moreover, the present invention relates to a kit for manufacturing a chip using such polymeric substrate. Moreover, the present invention relates to the use of a polymeric substrate having a glass-like surface, in particular an etched-glass-like surface for manufacturing a chip.

Polymeric substrate having an etched-glass-like surface and a microfluidic chip made of said polymeric substrate

A microfluidic device comprising in sequence first, second and third layers of plastics materials. A microfluidic circuit including a laterally extending microfluidic channel is formed at the interface between the first and second layers by surface structure in one or both of the first and second layers. A via is formed in the third layer for supplying or removing fluid to or from the microfluidic circuit. A conduit is formed in the second layer to provide fluid communication between the microfluidic channel and the via. A weld is formed at the interface between the second and third layers in a continuous closed path around the via and forms a fluid-tight seal for fluid flow between the via and the microfluidic circuit.

Microfluidic device and a method of manufacturing a microfluidic device

Growing community of inventors

Salzburg, Austria

Alfred Paris