Fresenius Medical Care Deutschland Gmbh

Alfred Gagel

Pascal Kopperschmidt

Andreas Maierhofer

Klaus Balschat

Reiner Spickermann

Malte Gross

Peter Kloeffel

Jochen Schneider

Olaf Nicholas

Tilman Staeblein

Ulrich Moissl

Gerhard Wiesen

Michael Koch

Benedict Glaser

Martin Thys

Thomas Nuernberger

Ralf Wamsiedler

Carsten Müller

Tobias Irrgang

Andreas Wüpper

Karsten Fischer

Helmuth Ender

Peter Klöffel

Tilman Stäblein

Stefan Kellermann

Jochen Popp

Liubov Smyslova

Dirk Hümmer

Dirk Huemmer

Steffen Kirchner

Thomas Nürnberger

Burkard Keller

Santer Zur Host-Meyer

Hans-Joachim Muench

Tobias Fritsche

Roland Ollinger

Daniel Hendreich

Peter Imhof

Michael Kulz

Haitham Ibrahim

Michael Külz

René Bauer

Hans-Joachim Münch

The invention relates to an extracorporeal blood treatment apparatus comprising a blood treatment unitthat is divided by a semipermeable membraneinto a first compartment, which is part of a fluid system II, and a second compartment, which is part of an extracorporeal blood circuit I. The invention also relates to a method for operating a blood treatment apparatus of this kind. The blood treatment apparatus according to the invention has a pressure-based checking devicewhich interacts with the control unitfor a valve deviceand is designed such that a fluid connection between an upstream portionA and a downstream portionB of a flow pathfor a special operating mode can only be established if the pressure-based checking devicedetects an operating state in which it is ensured that fluid in the flow pathfor a special operating mode flows towards a flow pathleading to a drain. This ensures that the fluid in question can only flow into the flow paththat leads to the drain, and cannot get into another flow pathin which fresh treatment fluid is located.

Extracorporeal blood treatment device

A method that regulates supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. An extracorporeal blood treatment apparatus that includes a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading. The selection of dialyzer parameters or blood parameters is therefore no longer necessary and the distinction between pre-dilution and post-dilution is also made obsolete.

Method for regulating the supply of substituate during extracorporeal blood treatment and extracorporeal blood treatment device comprising a unit for regulating the supply of substituate

The present invention relates to a dialysis machine that is configured to be equipped with an extracorporeal blood system comprising a dialysis solution system that is configured to be equipped with a dialyzer, wherein a mixing region, in particular a mixing chamber, is provided in which the fresh dialysis solution or a component thereof is located in the operation of the dialysis machine, with a concentrate line being in fluid communication with the mixing region, through which concentrate line concentrate can be conducted from a concentrate container into the mixing region, wherein at least two electrically conductive elements are arranged spaced apart from one another in or at the concentrate line or lines; that a measuring device is provided which is electrically connected to the conductive elements and which is configured to measure the conductance or a value correlated therewith between them; and that a control unit is provided which is configured to compare the measured value with a desired value, with a limit value, or with a desired value range.

Dialysis machine and method of operating a dialysis machine

A diagnosis method for a conductivity sensor for a dialysis fluid preparation apparatus and personal dialysis apparatus, that mix water, an A fluid and a B fluid in predetermined proportions respectively to prepare a dialysis fluid and measures the concentration of the prepared dialysis fluid by concentration measurement means is described. The diagnosis method and the respective apparatus is based in measuring the A fluid without the B fluid being present in the solution.

Dialysate concentration measurement sensor diagnosis

The present invention relates to a method for regulating supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. Moreover, the present invention relates to an extracorporeal blood treatment apparatus having a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading. The selection of dialyzer parameters or blood parameters is therefore no longer necessary and the distinction between pre-dilution and post-dilution is also made obsolete.

The present invention relates to a method of monitoring the bicarbonate content and the sodium content of a dialysis solution, wherein the dialysis solution is prepared while adding a bicarbonate component and an acidic sodium component, and wherein the method comprises the following steps:

Method of monitoring the bicarbonate content and the sodium content of a dialysis solution

A dialysis machine has a blood circuit, a blood pump, a dialyzer, a venous pressure sensor, a substituate line, and a control unit. The control unit can operate the blood pump in a first operating mode and in a special operating mode, and start the special operating mode after a trigger event. In the special operating mode, a blood pump conveying rate is controlled via a default value or regulated to a desired value, with the default or desired value being derived from a value determined before the started special mode or corresponding to the value. The presence of an obstacle is polled before the special mode, and depending on the presence thereof, the start of the special mode is blocked or delayed and/or the selection of the default value or the desired value on the presence of the obstacle differs from the selection without the presence of the obstacle.

Dialysis machine

A dialysis device having an extracorporeal blood circuit which has an arterial line having a blood pump and an arterial needle for connection to a patient, a venous line having a venous needle for connection to a patient and a dialyzer arranged between the arterial line and the venous line and having a blood chamber and a dialysis fluid chamber is provided. The dialysis device furthermore has a control unit and an extracorporeal blood pressure sensor which is arranged at the suction side of the blood pump. The control unit is configured such that a signal output takes place which indicates the presence of recirculation when a change in the signal of the sensor following a trigger event exceeds a threshold value.

Dialysis device having means for recognizing a shunt recirculation

The invention relates to a control unit () for detecting an overshoot of a first limit value (G) of a first blood concentration (B) in a first portion () of a dialysate discharge line () downstream of a dialysate chamber () of a dialyser () of a blood treatment device and upstream of a node point () at which a bypass line () bypassing the dialyser () leads into the dialysate discharge line (), wherein the bypass line () branches off, upstream of the dialysate chamber (), from a dialysate supply line () suitable for supplying dialysate from a dialysate source () to the dialysate chamber ().

Control unit for detecting blood in a dialysate discharge line of a blood treatment device, and blood treatment device

The invention relates to a method and to a device for determining an optimum dialysate flow Qfor an extracorporeal blood treatment and to a blood treatment device comprising a device 18 for determining an optimum dialysate flow Qd. The optimum dialysate flow Qdis determined on the basis of a relationship describing the dependence of the clearance K on the dialysate flow Q. The device according to the invention comprises a measurement deviceB for measuring at least one value which is characteristic of the clearance K, a calculation and/or evaluation unitA of the device according to the invention being configured in such a way that the clearance K is determined on the basis of the at least one value which is characteristic of the clearance. The calculation and/or evaluation unitA is configured in such a way that the optimum dialysate flow Qis determined from the relationship describing the dependence of the clearance K on the dialysate rate Qon the basis of the measured clearance K, or the optimum dialysate flow Qis determined from the measured clearance K.

Device and method for determining an optimum dialysate flow for an extracorporeal blood treatment with an extracorporeal blood treatment device

The present invention relates to a method of determining the pressure or of a parameter correlated with the pressure in an extracorporeal circuit of a blood treatment apparatus, in particular of a dialyzer, wherein at least one blood pump which is driven by at least one motor is located in the blood circuit, wherein the motor current of the named motor and the blood flow or a parameter correlated therewith is measured for determining the pressure or the parameter correlated therewith and wherein the pressure p or the parameter correlated therewith is calculated from the measured values.

Method of determining the pressure in an extracorporeal circuit

A dialysis machine has at least one filter for the filtration of dialysis liquid and a device for determining calcification of the dialysis machine. The device has one or more sensors configured and arranged to detect either downstream, or upstream and downstream, of the at least one filter an ion concentration or a parameter representative of the ion concentration or of its change of the dialysis liquid, of a solution serving the decalcification or of another measuring solution. The device for determining the calcification of the dialysis machine has an evaluation or calcification unit configured to determine the calcification of the dialysis machine based on the ion concentration or parameter value detected by the sensor or sensors.

Dialysis machine, and method of determining the calcification in a dialysis machine

The present invention pertains to Method for monitoring a dialysis treatment of a patient, preferably for monitoring a haemodialysis, haemodiafiltration and/or peritoneal dialysis treatment of a patient, the method including the steps of:

Method and device for monitoring an extracorporeal blood treatment of a patient

A container for dialysis concentrates, in particular acidic dry concentrates, has integral supporting elements. When these dry concentrates are dissolved directly by a dialysis machine to form liquid concentrates, the container must provide a volume of 4-12 liters. To impart the required stability to the container, the container includes the integral supporting elements, which manifest their supporting function only when the container is used on the dialysis machine.

Concentrate container having supporting elements

Method and apparatus for controlling the dialysate flow in a dialysis device. A change of the value of a control factor, caused by a variation of a property of the dialysate or of the blood or by a change of the dialysate flow, is determined in order to control the dialysate flow. The control factor is a measure for the exchange of substances via the dialyzer and thus the effectiveness of the dialyzer. If the change of the value of the control factor exceeds a limit, the dialysate flow is increased. On the other hand, the dialysate flow is reduced if the change of the value of the control factor falls short of the limit range.

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Litzendorf, Germany

Alfred Gagel