The Procter Gamble Company

The Proctor 'gamble Company

Other

Genencor International, Inc.

Alfred Busch

Johan Smets

Andre Cesar Baeck

Jean-Luc Philippe Bettiol

Christophe Laudamiel

Andre Christian Convents

Hugo Robert Denutte

Peter Marie Kamiel Perneel

Ivan Maurice Alfons Jan Herbots

Volker Schellenberger

Ayrookaran J Poulose

James T Kellis, Jr

Robert Mark Caldwell

Katherine D Collier

Michael Stanford Showell

Chanchal Kumar Ghosh

Christian G Paech

Joanne Nadherny

Donald P Naki

Ryohei Ohtani

Andr&eacute; Cesar Baeck

Maria Montserrat Sanchez-Pena

Marie Montserrat Sanchez-Pena

Ann Katrien Verschuere

James C Burckett St Laurent

Jean Wevers

Frederick E Hardy

Rafael Trujillo

Stanton Lane Boyer

Marcel Hombl&eacute;

Alan David Willey

James P Johnston

Peter Robert Foley

Kofi Ofosu-Asante

Christiaan A Thoen

Mary Vijayarani Barnabas

Christian R Barrat

Abdennaceur Fredj

Lynda Anne Jones

Young S Oh

Raphael Angeline Ceulemans

Don K Liu

Olivier Paquatte

André Cesar Baeck

Isabelle M De Groote

Finlay MacCorquodale

Finlay McCorquodale

Petrus Johannes Leeuwen

Petrus Johannes Van Leeuwen

Thierry Laurent Cachet

Andr&eacute;Cesar Baeck

Conny Erna Joos

Sardelis Kosmas

James C St Laurent

Kosmas Sardelis

Hans Raemdonck

Ann Katrien Marie Verschuere

James T Kellis

Maria Montserrat Appartement 81 Sanchez-Pena

The present invention relates to a product of reaction between an amino functional polymer comprising at least one primary and/or secondary amine and one or more active ingredient. By the present invention, there is provided a release of the active component over a longer period of time than by the use of the active itself.

Amine reaction compounds comprising one or more active ingredient

The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 ofsubtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 ofsubtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a subtitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 ofsubtilisin; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 ofsubtilisin; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.

Cleaning compositions containing multiply-substituted protease variants

The present invention relates to bleaching compositions comprising a protease variant. One bleaching composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of subtilisin in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274, and 275 of subtilisin; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a substitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265, or 274 of subtilisin, a bleaching agent; and one or more cleaning adjunct materials. Another bleaching composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of subtilisin; a bleaching agent; and one or more cleaning adjunct materials. Methods for using the bleaching compositions are also provided.

Bleaching compositions comprising multiply-substituted protease variants

The present invention relates to a product of reaction between a primary and/or secondary amine and one or more active ingredients. By the present invention, there is provided a release of the active component over a longer period of time than by the use of the active itself.

There is provided a process for producing particles of amine reaction product by means of an acid carrier. Processed amine reaction products and finished compositions incorporating such processed product are also herein provided.

Process for producing particles of amine reaction products

There is provided a process for producing particles of amine reaction product by means of a carrier having a melting point of less than 30&deg; C. optionally followed by a coating step. Processed amine reaction products and finished compositions incorporating such processed product are also herein provided.

Cleaning compositions, including laundry, dishwashing, hard surface cleaner, oral/dental cleaning compositions, comprising an oxidoreductase with an &agr;/&bgr;-hydrolase fold and a catalytic triad consisting of the amino acid residues serine, histidine and aspartic acid, which provide effective and efficient cleaning of colored and/or everyday body stains and/or soils and the sanitization of treated surface.

Cleaning compositions comprising an oxidoreductase

The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to position 103 of in combination with a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 1, 3, 4, 8, 9, 10, 12, 13, 16, 17, 18, 19, 20, 21, 22, 24, 27, 33, 37, 38, 42, 43, 48, 55, 57, 58, 61, 62, 68, 72, 75, 76, 77, 78, 79, 86, 87, 89, 97, 98, 99, 101, 102, 104, 106, 107, 109, 111, 114, 116, 117, 119, 121, 123, 126, 128, 130, 131, 133, 134, 137, 140, 141, 142, 146, 147, 158, 159, 160, 166, 167, 170, 173, 174, 177, 181, 182, 183, 184, 185, 188, 192, 194, 198, 203, 204, 205, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 222, 224, 227, 228, 230, 232, 236, 237, 238, 240, 242, 243, 244, 245, 246, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 265, 268, 269, 270, 271, 272, 274 and 275 of ; wherein when said protease variant includes a substitution of amino acid residues at positions corresponding to positions 103 and 76, there is also a subtitution of an amino acid residue at one or more amino acid residue positions other than amino acid residue positions corresponding to positions 27, 99, 101, 104, 107, 109, 123, 128, 166, 204, 206, 210, 216, 217, 218, 222, 260, 265 or 274 of ; and one or more cleaning adjunct materials. Another cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid residue positions corresponding to positions 62, 212, 230, 232, 252 and 257 of ; and one or more cleaning adjunct materials. Methods for using the cleaning compositions are also provided.

The present invention relates to a modified enzyme which comprises a catalytically active amino acid sequence of a cellulolytic enzyme linked to an amino acid sequence comprising a Cellulose Binding Domain (CBD) having a relative binding constant (Kr-a) for binding to amorphous cellulose higher than 2.4 l/gcellulose, preferably higher than 3.5 l/gcellulose, more preferably higher than 4 l/gcellulose, for selective binding and hydrolysis of amorphous cellulose of cotton containing fabrics in a laundry and/or fabric care application. The present invention further relates to laundry detergent and/or fabric care compositions comprising this modified enzyme.

Laundry detergent and/or fabric care compositions comprising a modified cellulase

Cleaning compositions, including laundry, dishwashing, hard surface and/or oral/dental compositions comprising a cytochrome, particularly cytochrome P450. Said compositions provide effective and efficient cleaning of colored and/or everyday body stains and/or soils and provide sanitization of the treated surfaces. When formulated into a laundry detergent composition, the present invention provides fabric realistic item cleaning and enhanced whitening.

Cleaning compositions comprising a cytochrome

Modified enzymes which comprise a catalytically active amino acid sequence of an enzyme, linked via a non-mino acid linking region to an amino acid sequence comprising a Cellulose Binding Domain. The present invention further relates to laundry detergent and/or fabric care compositions comprising such modified enzymes. These compositions provide a higher effective concentration of the enzyme at its substrate location and therefore, improved enzymatic benefits.

Laundry detergent and/or fabric care compositions comprising a modified enzyme

There is provided a process for producing particles of amine reaction product by means of a carrier having a melting point between 30 degrees Celsius and 135 degrees Celsius, optionally followed by a coating step. Processed amine reaction products and finished compositions incorporating such processed product are also herein provided.

Process for producing particles of amine reaction product

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Londerzeel, Belgium

Alfred Busch