Aventis Pharma Deutschland, Gmbh

Hoechst Aktiengesellschaft

Sanofi-a Ventis Deutschland Gmbh

Hoechst Marion Roussel Deutschland Gmbh

Alfons Enhsen

Heiner Glombik

Werner Kramer

Elisabeth Defossa

Hubert Heuer

Wendelin Frick

Andreas W Herling

Thomas Klabunde

Hans-Joerg Burger

Erich Von Roedern

Dieter Kadereit

Karl Schoenafinger

Eugen Falk

Gunther Wess

Karl-Ulrich Wendt

Siegfried Stengelin

G Unther Wess

Andreas Gerhard Weichert

Jan-Robert Schwark

Hans Jochen Lang

Reinhard Kirsch

Stefan Peukert

Karl-Heinz Baringhaus

Hans-Willi Jansen

Armin Bauer

Joerg Rieke-Zapp

Bernd Neises

Stefan M Ullner

Eugene Falk

Ralf Watkowiak

Karl Ulrich Wendt

Erich Von Reodern

Karl-Urlich Wendt

The invention relates to acyl-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I, in which the radicals have the stated meanings, and the physiological tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example for the treatment of type II diabetes.

Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments

The invention relates to acyl-4-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. The invention particularly relates to compounds of formula I, in which the radicals have the given meanings described herein, and to their physiologically tolerated salts and processes for preparing them. The compounds are, for example, suitable for use as antidiabetics.

Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use

The invention relates to compounds of the formula I in which the radicals are defined as specified, and also to their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.

Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use

The invention relates to acyl-3-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. The invention relates to compounds of formula I, in which the radicals have the given meanings, and to their physiologically tolerated salts and processes for preparing them. The compounds are, for example, suitable for use as antidiabetics.

Acyl-3-carboxyphenylurea derivatives, processes for preparing them and their use

Substituted benzothiepine 1,1-dioxide derivatives of formula I:in which R, R, R, R, Rand Z have the meanings indicated, and their physiologically tolerable salts and physiologically functional derivatives and a process for their preparation are described. The compounds are suitable, for example, as hypolipidemics.

Benzothiepine 1, 1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use

Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments

Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use

Substituted 1,3-diaryl-2-pyrid-2-yl-3-(pyrid-2-ylamino)propanol derivatives, process for their preparation, pharmaceuticals comprising these compounds and their use

The invention relates to substituted benzo(b)thiepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention relates to compounds of formula (I), wherein R , R , R , R , R and Z have the cited descriptions, to the physiologically compatible salts, to physiologically functional derivatives, and to a method for the production thereof. The compounds are suited, for example, as hypolipidemic agents.

Benzo(b)thiepine-1,1-dioxide derivatives, a method for the production thereof, medicaments containing these compounds, and their use

Substituted benzothiepine 1,1-dioxide derivatives of formula I:

Propanolamine derivatives linked to bile acids, processes for their preparation, pharmaceuticals comprising these compounds, and their use

Substituted phenylalkenoylguanidines, processes for their preparation, uses as medicaments or diagnostics, and medicaments containing them are described. The invention relates to substituted phenylalkenoylguanidines and their pharmaceutically tolerable salts and physiologically functional derivatives of the formula ##STR1## in which the radicals have the meanings indicated, and their physiologically tolerable salts and processes for their preparation. The compounds are suitable as medicaments for the prophylaxis or treatment of gallstones.

Substituted phenylalkenoylguanidines, process for their preparation, and

The present invention is concerned with new hypolipidemic compounds, with processes and novel intermediates for their preparation, with pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, such as atherosclerosis. Compounds of the formula (I): ##STR1## wherein R.sup.1 to R.sup.10 and X are as defined in the Specification and useful as hypolipidemic compounds.

Hypolipidemic 1,4-benzothiazepine-1,1-dioxides

A device for establishing a flange connection, having a bearing which can act on a first flange, a counter-bearing which can act on a second flange, and a connecting lever between the two bearings is described. The invention is distinguished by the fact that the connecting lever is a lever with a drawing element. The drawing element and the lever each have a first and second end. The drawing element's first end engages the bearing and its second end jointedly mounts in between the first and second ends of the lever. The counter-bearing has at least one contact location for the first end of the lever and a recess for the drawing element.

Closure systems for chromatographic columns

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Büttelborn, Germany

Alfons Enhsen