Boehringer Ingelheim Animal Health USA Inc.

Genzyme Corporation

Sanofi Pasteur Sa

Boehringer Ingelheim Vetmedica Gmbh

Sanofi Pasteur Inc.

Alexis Guy André Lucien Parisot

Guillaume Rigaut

Pradeep K Dhal

Jean Haensler

Philippe Talaga

Marie Garinot

Patricia Probeck-Quellec

Christine Michele Pierrette Andreoni

Celine Loss-Dunod

Karelle De Luca

Lydie Remolue

Jean-François Cotte

Véronique Chambon

Pradeep K Dahl

The present invention provides for novel immunological and vaccine formulations comprising a newly applied non-crosslinked polyacrylic acid polymer adjuvant. The adjuvants may be combined with a wide variety of immunogens to produce vaccines that are safe and effective when administered to a wide range of target animals. The immunogens may include, but are not limited to: inactivated pathogens, attenuated pathogens, subunits, recombinant expression vectors, plasmids or combinations thereof. The animals may include, but are not limited to: humans, murine, canines, felines, equines, porcines, ovines, caprines and bovines.

Immunogenic formulations comprising linear or branched polyacrylic acid polymer adjuvants

The present invention relates to non-mercurial preservatives, including antimicrobial polyamide polymers and octenidine, and to methods of use thereof to produce preservative-containing multi-dose formulations. The preservative-containing multi-dose formulations exhibit resistance to one or more contaminating microorganisms, and have advantageous properties with respect to long term stability of biological and small molecule active ingredients.

Multi-dose compositions containing an antimicrobial polyamide or octenidine preservative

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Lyons, France

Alexis Guy André Lucien Parisot