Fresenius Vial Sas

Alexandre Guerrini

Pauline Cottin

Maxime Buriat

Frank Doesburg

Maarten Nijsten

Maxime Burlat

A method for performing a continuous infusion process includes delivering a first fluid through a first delivery line at a first flow rate using a first infusion device in a first phase, and delivering a second fluid through a second delivery line at a second flow rate using a second infusion device in a second phase following the first phase. A relay device connected to said first and second delivery lines configured to discharge first or second fluid to an outlet delivery line connected to the relay device, the outlet delivery line having a predefined delivery volume. Subsequent to the delivery of the first fluid in the first phase, the second infusion device in an intermediate phase is operated for a predetermined delivery time to deliver the second fluid at the first flow rate, the predetermined delivery time determined taking the predefined delivery volume into account.

Method and system for performing a continuous infusion process

A system for providing multiple infusions to a patient (P), the system comprises a multiplicity of infusion devices () for administering a multiplicity of medical fluids through an infusion line () of an infusion set () to the patient (P), and a control device () for controlling the multiplicity of infusion devices (). Herein, the control device () comprises a multiplex module () configured to multiplex the multiplicity of medical fluids for a multiplexed administration of the medical fluids through said infusion line () of the infusion set (), the multiplex module () comprising a scheduling module () configured to define at least two packets, each packet comprising at least one medical fluid out of the multiplicity of medical fluids, and to arrange the at least two packets in a sequence for administration of the medical fluids of the at least two packets. In this way a system for providing multiple infusions to a patient is provided which allows for an efficient, yet reliable administration of multiple infusions while at the same time reducing the risks for errors. An advantage of multiplexing is reduction of the number of lumens with associated reduction of infection risks and discomfort.

System for providing multiple infusions to a patient

The invention relates to a control device for controlling the administration of propofol to a patient according to the preamble of claimand to a method for controlling the administration of propofol to a patient according to the preamble of claim. With a method of this kind a bispectral index (BIS) target value is set which shall be, at least approximately, reached within a patient. A controller then computes a recommended infusion rate of propofol based on the target BIS value and further based on a measured propofol level of the patient for administering propofol to the patient. The controller herein comprises a model unit for computing the recommended infusion rate such that, using the model unit for determining the propofol sensitivity of a patient by means of a mathematical model taking into account the bispectral index (BIS) value and optionally the measured propofol level as input variables, the recommended infusion rate for administering propofol to the patient to achieve the BIS target value may be determined.

Control device for controlling the administration of propofol to a patient

In a method for controlling the administration of insulin to a patient, a target glucose level is set and a controller computes a recommended infusion rate based on the target glucose level and a measured glucose level of a patient for administering insulin to the patient. The controller uses a controller gain for computing the recommended infusion rate. Herein, an insulin sensitivity of the patient is determined using a mathematical model taking into account the measured glucose level and an actual infusion rate of insulin administered to the patient and, based on the insulin sensitivity, the controller gain of the controller is determined. In this way a method for controlling the administration of insulin to a patient is provided which in a reliable, computationally efficient manner allows for maintaining a patient's blood glucose level at or around a desired target glucose level.

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Fontaine, France

Alexandre Guerrini