Evonik Degussa Gmbh

Alexandra Lerchner

Thomas Haas

Arne Skerra

Jan Christoph Pfeffer

Steffen Schaffer

Wolfgang Kroutil

Volker Sieber

Katrin Grammann

Kai Doderer

Markus Pötter

Claudia Rollmann

Johann H Sattler

Katharina Christin Tauber

Broder Rühmann

Broder Ruehmann

Christian Rausch

Markus PÖTTER

A method including the steps a) providing a primary alcohol of the formula HO&#x2014;(CH)&#x2014;R, where Ris &#x2014;OH, &#x2014;SH, &#x2014;NHor &#x2014;COOR; x is at least 3; and Ris H, alkyl or aryl, b) oxidizing the primary alcohol by contacting it with an NAD(P)-dependent alcohol dehydrogenase, and c) contacting the oxidation product of step a) with a transaminase, where the NAD(P)-alcohol dehydrogenase and/or the transaminase is a recombinant or isolated enzyme. A whole cell catalyst for carrying out the method. The use of such a whole cell catalyst for oxidizing a primary alcohol.

Oxidation and amination of primary alcohols

The invention relates to a method for the amination of at least one keto group in a multicyclic ring system comprising at least one keto group into an amino group, using at least one enzyme E having transaminase activity.

Method for producing multicyclical ring systems carrying amino groups

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Neufahrn bei Freising, Germany

Alexandra Lerchner