Isis Innovation Limited

Imaxio Sa

Alexandra Jane Spencer

Matthew Guy Cottingham

Adrian Vivian Sinton Hill

Fergal Hill

There is provided a fusion protein or a polynucleotide sequence encoding said fusion protein that comprises first and second domains, wherein the first domain of the fusion protein comprises an amino acid sequence having at least 70% sequence identity to the amino acid sequence of SEQ ID NO: 1, or a fragment thereof comprising at least 20 consecutive amino acids thereof; and wherein the second domain of the fusion protein comprises a mycobacterial antigen or an antigenic fragment thereof. Also provided are corresponding therapeutic uses thereof for the protection of primates against mycobacterial infections.

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Oxford, United Kingdom

Alexandra Jane Spencer