Systagenix Wound Management, Limited

Kci Licensing, Inc.

Kci Usa, Inc.

3m Innovative Properties Company

Alexander Waite

Christopher Brian Locke

Craig Delury

Breda Mary Cullen

Derek Silcock

Katie Bourdillon

Benjamin Andrew Pratt

Justin Alexander Long

Kristine M Kieswetter

William Pigg

Prathamesh Madhav Kharkar

Justin A Long

Daniel Parker

Katherine A Bourdillon

Carrina Ward

Clinton Hill

Kyle Turton

Adam Whaites

Joy Thistlethwaite

Derek Walter Silcock

This disclosure includes wound dressings and systems with remote oxygen generation for topical wound therapy and related methods. Some systems include a dressing for facilitating delivery of oxygen to the target tissue, the dressing having: a first manifold that defines a plurality of gas passageways and is configured to allow communication of oxygen to the target tissue; a gas-occlusive layer configured to be disposed over the first manifold and coupled to tissue surrounding the target tissue such that: an interior volume is defined between the gas-occlusive layer and the target tissue; and the gas-occlusive layer limits escape of oxygen from the interior volume between the gas-occlusive layer and the tissue surrounding the target tissue; a container outside the interior volume, the container having a sidewall that defines a chamber configured to be in fluid communication with the interior volume; and an oxygen-generating material disposed within the chamber of container and configured to release oxygen when exposed to water.

Wound dressings and systems with remote oxygen generation for topical wound therapy and related methods

The present disclosure provides wound dressing compositions that stimulate nitric oxide production in a wound upon application. The wound dressing composition includes a first layer comprising collagen and an oxidized cellulose and a second layer comprising a nitrite source. Also disclosed herein are kits comprising the wound dressing compositions of the present technology.

Nitric oxide producing collagen/ORC dressing

The wound dressing described herein can be used as a contact layer dressing. The wound dressing can be positioned between a wound bed and a secondary dressing. The wound dressing can include a layered construction. Each of the layers can include a bioresorbable sponge enclosed within a collagen-based film. The wound dressing can include a plurality of fluid channels that enable fluid flow from the wound bed toward the environment-face side of the wound dressing.

Multilayered primary contact wound dressing

A wound dressing includes an inelastic absorbent layer, an elastic film, and a plurality of welds. The inelastic absorbent layer is configured to absorb wound fluid and has a first side and a second, wound-facing side. The elastic film is configured to elastically stretch when a stretching force is applied to the wound dressing and elastically recover when the stretching force is removed. The plurality of welds fix the elastic film to the first side of the inelastic absorbent layer such that the elastic film and the inelastic absorbent layer elastically stretch and elastically recover as a unit.

Wound dressing with welded elastic structure

A medical delivery device for treating a tunneling wound includes an outer sleeve, a plunger, and a hollow tube extending through an opening in the plunger. The plunger is configured to deliver a wound treatment material from an inner cavity of the outer sleeve, through a cavity opening on the outer sleeve, and into the tunneling wound. The hollow tube is configured to deliver a fluid to the wound treatment material after insertion into the tunneling wound. In some embodiments, the medical delivery device may further include a flap disposed on the outer sleeve. The flap may be reconfigurable between a closed position in which the flap is configured to shield the cavity opening, and an open position in which the flap is configured to allow the wound treatment material to be ejected through the cavity opening.

Material application system for tunneling wounds that allows co-delivery of solutions

A dressing configured to be positioned adjacent to a tissue site is disclosed herein. The dressing may include oxidized regenerated cellulose (ORC), collagen, and at least one nutrient including glutamine. Methods of treating a tissue site are also disclosed herein.

Nutrient-enriched dressing

Wound dressing compositions comprising of a bioresorbable sponge encapsulated within a polysaccharide envelope. The bioresorbable sponge is preferably comprised of collagen and oxidised regenerated cellulose. The outer polysaccharide envelope is preferably comprised of chitosan. The outer polysaccharide envelope functions to modulate the rate at which the bioresorbable sponge breaks down within a wound.

Collagen/ORC dressing encapsulated within a bioresorbable envelope

Dressings are provided herein having a manifold and a biopolymer layer. The configuration and/or compressibility of the manifold and the biopolymer layer can allow for reduced tissue ingrowth and promote wound healing. Methods of making and using the dressings are also provided herein.

Dressings for reduced tissue ingrowth

A dressing (as well as uses, systems, and methods including such dressing) is provided that includes a contact layer with a first surface configured to contact a tissue site in a subject and includes a scaffold configured to structurally support the contact layer, where the contact layer includes a bioresorbable material. The dressing may advantageously exhibit protease-modulating activity under physiological conditions.

Bioresorbable dressing with structural support

A polyurethane foam wound dressing, the foam integrally comprising an oxidoreductase enzyme and a substrate for the enzyme. The foam is produced by mixing a polyurethane polymer, water, an oxidoreductase enzyme and substrate for the enzyme and drying the resulting product.

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Cowling, United Kingdom

Alexander Waite