N.i Medical Ltd.

Alexander Tsoglin

Efim Frinerman

Yafim Frinerman

A method and a system for non-invasively determining at least one main cardiorespiratory parameter of an individual, such as the Stroke Volume, at least one parameter characterizing balance of the extracellular fluid in the body (such as the Index Balance), and for diagnostics of blood circulatory problems and/or failures of cardiac functions. The method for determining the main cardiorespiratory parameter comprises the steps of attaching at least two electrodes to the individual's body in a manner enabling to obtain electrical bioimpedance measurements of the whole individual's body, passing an alternating current with a stable and constant amplitude through the electrodes, measuring the integral bioimpedance as the result of the current flow; simultaneously separating an active component from the integral bioimpedance; calculating the cardiorespiratory parameter of the individual from the obtained active component, using an empiric formula applicable to integral bioimpedance measurements. The calculation is based on obtaining a number of values of the parameter for a number of cardia cycles during a respiratory cycle, and computing an average of the cardiorespiratory parameter during a single respiratory cycle.

Method and system for non-invasive determination of the main

A medical device, utilizing a non-invasive method for determining the main cardiorespiratory parameters of a patient's body, and employing a method of operation wherein two or four electrodes are applied to the patient's body in a manner enabling integral bioimpedance measurements of the total body of a patient to be effected. High stability amplitude alternating current is passed through the electrodes into the body so as to obtain an integral impedance curve of the body and derive therefrom simultaneous automatic separation of an active component. The desired cardiorespiratory parameters of the body are calculated from the active component of the integral bioimpedance, using empiric formulae applicable to integral bioimpedance measurements; the calculation being accomplished based on the average data obtained during a respiration cycle.

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Beer Yakov, Israel

Alexander Tsoglin