Abiomed, Inc.

Massachusetts Institute of Technology

The Brigham and Women's Hospital, Inc.

Alexander Ship

Zhenghong Tao

Elazer Reuven Edelman

Ahmad El Katerji

Steven F Keller

Noam Josephy

Brian Yale Chang

Qing Tan

Sonya Sanat Bhavsar

Christian Moyer

Christopher Zarins

Glen Robert Fantuzzi

Christopher Nason Korkuch

Robert Fishman

Robert Swierczek

Qingchao Kong

Soumen Das

Zenghong Tao

Steven Keller

A blood pump with a stator and rotor wherein the rotor is assembled by bonding the stator components with epoxy. The bonding surfaces of the rotor components are primed with a silane-based primer to improve adhesion between the primer and the rotor components by rendering such surfaces hydrophobic. A bonding surface of one of the stator yoke or the stator sleeve, or both, is treated with a primer that improves wettability of the bonding surface and improves bonding of the epoxy to the binding surface. The device has a bonding surface adhered to epoxy in which a primer was applied on such bonding surface prior to introducing epoxy onto the bonding surface. In addition to improved bond strength, hydrophobic surface would control moister ingress.

Blood pump with improved leakage control

Systems and methods for providing a blood pump system having a variable stiffness distal extension are disclosed. A variable stiffness distal extension may have at least one section of continuously varying stiffness, resulting in a stiffness profile that decreases in a distal direction along a length of the distal extension. The varying stiffness may be accomplished by varying one or more radial dimensions of the extension. For example, in some implementations, an outer diameter of a distal extension may decrease along at least a portion of a distal extension. The distal extension may include a lumen configured to receive a longitudinally extending element.

Variable-stiffness distal extension for a blood pump system

The systems and methods described herein determine metrics of cardiac performance via a mechanical circulatory support device and use the cardiac performance to calibrate, control and deliver mechanical circulatory support for the heart. The systems include a controller configured to operate the device, receive inputs indicative of device operating conditions and hemodynamic parameters, and determine vascular performance, including vascular resistance and compliance, and native cardiac output. The systems and methods operate by using the mechanical circulatory support device (e.g., a heart pump) to introduce controlled perturbations of the vascular system and, in response, determine heart parameters such as stroke volume, vascular resistance and compliance, left ventricular end diastolic pressure, and ultimately determine native cardiac output.

Systems and methods for determining cardiac performance

Distal extension for a blood pump system

An introducer sheath for the insertion of a medical device into a blood vessel having an expandable sheath. The sheath has a length, a thickness, and proximal and distal ends. The expandable sheath has a frame extending longitudinally between the proximal and the distal ends, and having an exterior surface and an interior surface that forms an interior lumen along the length of the frame. The frame is configured to achieve an expanded state and a contracted state, the expanded state forming an expanded cross-section in the lumen for passing a medical device therethrough. The frame has a smooth coating about the exterior surface and protrusions extending into the lumen along the interior surface. The introducer sheath can be introduced into a patient in the contracted state, with the distal end of the introducer sheath prevented from moving in the proximal direction by an abutment against a dilator end surface.

Expandable introducer sheath for medical device

Growing community of inventors

Danvers, MA, United States of America

Alexander Ship