Evonik Degussa Gmbh

Evonik Operations Gmbh

Alexander Reth

Brigitte Bathe

Stephan Hans

Wilfried Claes

Stefan Pelzer

Florian Böhl

Andreas Burkovski

Monika Flügel

Nadja Jessberger

Frank Thiemann

Reinhard Krämer

Gerd Seibold

Alexander Henrich

Andreas Kappel

Emeka Ignatius Igwe

Michelle Dargatz

Michaela Weissmann

A process for preparing L-amino acids employing coryneform bacteria in which the AmtR regulator has been attenuated is provided. Recombinant bacteria, polynucleotides and vectors corresponding to or having the attenuated AmtR regulator are disclosed.

Process for preparing L-amino acids

The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.

Microorganism and method for the fermentative production of an organic-chemical compound

The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.

Variants of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase

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Bielefeld, Germany

Alexander Reth