Molecular Health Gmbh

Alexander Picker

Stephan Brock

David B Jackson

Guillaume Taglang

Alexander Zien

Theodoros Soldatos

Martin Stein

Bernhard Sulzer

The present disclosure relates to systems and methods for bioinformatics and data processing. In particular, in a first aspect, the present disclosure relates to methods and systems for generating a personalized treatment guideline for a patient and for selecting a treatment for a patient. In another aspect, the present disclosure relates to methods and systems for selecting patients for a clinical trial of a treatment. The invention resolves cases in which patients have more than one 'actionable' aberration by combining the patient-specific molecular information and the treatment-specific molecular information further with a clinico-molecular disease model, specifically a scoring of genes and/or proteins that represents several aspects of their involvement into the disease. In this way, treatments and patients can be prioritized that are most likely to impact or impacted by the disease mechanism, respectively.

Systems and methods for clinical decision support

Growing community of inventors

Heidelberg, Germany

Alexander Picker