Nanohmics, Inc.

Syfr, Inc.

Alexander P Greis

Chris W Mann

Steve M Savoy

Daniel R Mitchell

Jeremy J John

Kyle W Hoover

Elzbieta A Ledwosinska

Paul Argus Parks

Shazi S Iqbal

Michael Mayo

Austin Ferrie

Kieran Lerch

An integral field spectral imager has a plurality of optical homogenizers. Each optical homogenizer is in-register with a corresponding different superpixel in a superpixel array and is configured to spatially homogenize incident EMR and to pass the spatially homogenized EMR to a spectral filter in an array of spectral filters, thence to the in-register, corresponding different superpixel. Baffles are included to maximize confinement of the spatially homogenized EMR passed by a single optical homogenizer to the in-register, corresponding different superpixel so as to minimize crosstalk between superpixels. Optical homogenizers and baffles are designed to produce a pattern of homogenized EMR on a superpixel, regardless of where incident EMR is received on an optical homogenizer. Methods for using embodiments of the spectral imager in a variety of spectral bands in the EMR spectrum enable determining spectral information about incident EMR.

Integral field spectral imager

Methods and sensors for the detection, identification, and quantification of one or more gas species, including volatile organic compounds, in a test sample are described. Methods employ gas sensors comprising a diffusion matrix present on the sensor surface. A gas analyte in a test sample diffuses through the matrix and is detected upon interaction of the analyte with the sensor. A response profile of a gas sensor to a gas analyte in the test sample is compared to a control gas sensor response profile determined in a similar manner for a known gas species. Comparisons of test sample and control sample sensor response profiles enable detection, identification, and quantification of a gas species analyte in a test sample.

Methods for detecting and quantifying gas species analytes using differential gas species diffusion

An apparatus comprises a housing defining a chamber that has a liquid disposed therein, and a sensor submerged in the liquid. The sensor comprises a porous conductive film on a substrate, and the film comprises chemiresistive semiconducting metal oxide structures. The sensor also comprises an electrode pair operably connected to the porous conductive film for generating electric current in the film and for detecting a change in an electrical property of the film. The apparatus can be used to detect, identify, and quantify ions and molecules in a liquid sample. Molecules and ions, in a liquid sample, that interact with the porous conductive film can cause a change in an electrical property of the film. The change in electrical property of the film can be correlated with the presence and amount of the molecules or ions.

Sensor and methods for detecting and quantifying ions and molecules

Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of a gas sensor to a control sample of a known interrogator gas is determined. The gas sensor is exposed to a test sample then to a second sample comprising the known interrogator gas, and a test sample response profile of the gas sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.

Methods for detecting and quantifying analytes using gas species diffusion

Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of an ion sensor to a control sample of a known interrogator ion is determined. The ion sensor is exposed to a test sample then to a second sample comprising the known interrogator ion, and a test sample response profile of the ion sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.

Methods for detecting and quantifying analytes using ionic species diffusion

A self-contained sample processing cartridge, is disclosed. The sample processing cartridge includes a first member that includes a receiver to receive a sample specimen slide. The cartridge may also include a second member that closes on the first member to form a chamber inside the cartridge. The sample specimen slide forms a surface of the chamber. Placing the slide in the cartridge effectively completes the chamber of the cartridge. In one embodiment, the receiver of the first member includes an open region adjacent which the specimen slide is received. The second member includes a plurality of fluid inputs and at least one fluid output. The plurality of fluid inputs couples to the chamber by a plurality of channels respectively therebetween. In one embodiment, at least one of the plurality of channels may include a reagent reservoir and at least one of the plurality of channels includes a dissolvable blocking reservoir.

Growing community of inventors

Austin, TX, United States of America

Alexander P Greis