Intercell Ag

Alexander Otava

Frank Mattner

Michael Buschle

Wolfgang Zauner

Christoph Klade

Oresta Vytvytska

Sandra Zinke

Helen Kirlappos

Described is a method for isolating Hepatitis C Virus peptides (HPs) which have a binding capacity to a MHC/HLA molecule or a complex comprising said HCV-peptide and said MHC/HLA molecule characterized by the following steps: &#x2014;providing a pool of HCV-peptide, said pool containing HCV-peptides which bind to said MHC/HLA molecule and HCV-peptides which do not bind to said MHC/HLA molecule, &#x2014;contacting said MHC/HLA molecule with said pool of HCV-peptides whereby a HCV-peptide which has a binding capacity to said MHC/HLA molecule binds to said MHC/HLA molecule and a complex comprising said HCV-peptide and said MHC/HLA molecule is formed, &#x2014;detecting and optionally separating said complex from the HCV-peptide which do not bind to said MHC/HLA molecule and optionally isolating and characterizing the HCV-peptide from said complex.

Method for isolating hepatitis C virus peptides

Growing community of inventors

Vienna, Austria

Alexander Otava