Glucovista Inc.

Alexander Ostritsky

Yonatan Gerlitz

Efraim Landa

Rotem Gerlitz

Embodiments of the present methods measure a concentration of a substance, such as glucose, in a body. The described embodiments change the temperature of the surface of a body from a first temperature to a second temperature, then change the temperature of the surface of the body from the second temperature back to the first temperature, and measure a first amount of infrared ('IR') radiation absorbed or emitted from the surface of the body in a first wavelength band, and a second amount of IR radiation absorbed or emitted from the surface of the body in a second wavelength band at predetermined time intervals during the time period that the temperature of the surface of the body changes from the second temperature back to the first temperature. The described embodiments also measure a temperature at the surface of the body and an ambient temperature. A normalized ratio parameter is calculated from the four measurements, and the concentration of the substance in the body is determined by correlating the normalized ration parameter with the body surface temperature and the ambient temperature.

Method for non-invasive analysis of a substance concentration within a body

A substance concentration analysis method includes calculating a difference for the particular time between a first measured amount of mid-infrared (MIR) radiation absorbed by or emitted from a body in a first wavelength and a second measured amount of MIR radiation absorbed by or emitted from the body in a second wavelength, calculating a quotient including a dividend based on the difference divided by a divisor based on a dT/dt value, and calculating the concentration of the substance in the body based on a correlation with the quotient.

Substance concentration analysis methods and apparatuses

A concentration correction system includes an infrared detector and components that produce an aggregate emission of infrared radiation. A mirror assembly includes a mirror and is changeable between a correcting configuration and a measuring configuration. In the correcting configuration, the mirror produces a mirror signal incident on the detector. The mirror assembly also obstructs external body infrared radiation from reaching the detector. In the measuring configuration, the mirror assembly allows the external body infrared radiation onto the detector. A concentration correction method includes receiving external body infrared radiation and simultaneously receiving a first portion of the aggregate emission. A measurement value indicative of concentration is recorded from the detector. A second portion of the aggregate emission reflected with the mirror and produces a mirror signal incident on the detector. A correction value corresponding to the mirror signal is recorded from the detector and used to correct the measurement value.

Growing community of inventors

Rishon Lezion, Israel

Alexander Ostritsky