The State University of New York

Alexander N Cartwright

Frank V Bright

Albert Titus

Joseph A Gardella

Rena Bizios

Wesley L Hicks, Jr

Robert Hard

Rachel M Bukowski

Jamson S Lwebuga-Mukasa

Bahattin Koc

Vamsy P Chodavarapu

A detection device and a method of detection are disclosed. The device may have a sensor array, a detector array, and a sensor controller. The sensor array may have a plurality of sensors, each sensor being responsive to a different analyte of interest. Each sensor may also be able to emit electromagnetic energy. For example, one or more of the sensors may include an LED. One or more of the sensors may include a sensing compound within a xerogel, which is responsive to an analyte of interest. In the method, one of the sensors is turned on, and one or more of the detectors are activated to receive electromagnetic energy emitted from the sensor.

Temporally addressable detection array

A sensor has a sensor substance, an electromagnetic energy source, and a detector. The sensor substance may be able to emit electromagnetic energy different than that provided by the energy source when an analyte of interest is in contact with the sensor substance and electromagnetic energy is received by the sensor substance. The energy source and the detector may be provided on the same side of the sensor substance. In a method according to the invention, a determination may be made as to whether an analyte is present in a sample. Such a method may provide a sensor, such as that described above. Electromagnetic energy may be provided to the sensor substance using the energy source, and the sensor substance may be contacted with a sample. Electromagnetic energy may be emitted from the sensor substance and received at the detector. The detector may provide a signal indicating the type of electromagnetic energy emitted from the sensor substance. The signal from the detector may be analyzed to determine whether the analyte was detected.

Sensor and method of sensing having an energy source and detector on the same side of a sensor substance

pH-change sensors and related methods are disclosed. One such sensor may have a first ion-sensitive transistor-operational-transconductance-amplifier (the 'first IOTA') and a second ion-sensitive transistor-operational-transconductance-amplifier (the 'second IOTA'). Each IOTA may have an ion-sensitive transistor, a load transistor, and an output. In each IOTA, the drain region of the ion-sensitive transistor may be connected to the drain region of the load transistor. A differential sensor may be connected to the IOTAs, and an output from the differential sensor may indicate a voltage difference between the IOTA outputs. The output from the differential sensor may be used to provide an indication of a change in pH.

pH-change sensor and method

The present invention provides a reepithelialization/wound healing implant device comprising a barrier layer and one or more polymer layers doped with agents that promote one or more processes in reepithelialization/wound healing. The implant: [a] provides a temporary mechanical/chemical barrier to species within the external environment that inhibit epithelial migration (e.g., unbalanced production/expression of granulation tissue, inhibitory proteins); [b] biodegrades at an appropriate rate while tissue remodeling is occurring; and [c] delivers active cytokines and growth factors in a choreographed pattern to promote reepithelialization.

Resorbable laminated repair film and method of using same

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Williamsville, NY, United States of America

Alexander N Cartwright