University of California

Alexander Mo

Ratneshwar Lal

Preston B Landon

Joon Bok Lee

Gennadi V Glinskii

Michael Taeyoung Hwang

Srinivasan Ramachandran

Brian Meckes

Preston Boone Landon

Methods, systems, and devices are disclosed for fabricating and implementing nanoscale and microscale structured carriers to provide guided, targeted, and on-demand delivery of molecules and biochemical substances for a variety of applications including diagnosis and/or treatment (theranostics) of diseases in humans and animals. In some aspects, a nanostructure carrier can be synthesized in the form of a nanobowl, which may include an actuatable capping particle that can be opened (and in some implementations, closed) on demand. In some aspects, a nanostructure carrier can be synthesized in the form of a hollow porous nanoparticle with a functionalized interior and/or exterior to attach payload substances and substances for magnetically guided delivery and controlled release of substance payloads.

Nanostructured carriers for guided and targeted on-demand substance delivery

Methods, systems, and nano-sensor devices are disclosed for detecting or discriminating nucleic acids with a single nucleotide resolution based on nucleic acid strand displacement. The detection can be made by time-lapse fluorescence measurements or by electro-based graphene FET, which can be combined with wireless communication to provide real-time transmission of the detected signals.

Nano-sensors for nucleic acid detection and discrimination

Growing community of inventors

La Jolla, CA, United States of America

Alexander Mo