Case Western Reserve University

Alexander M Jordan

Gary E Wnek

LaShanda T J Korley

Disclosed herein are biomaterials that include a plurality of fibers embedded in a matrix of hydrogel material. The plurality of fibers and hydrogel material are formed during one process step. In one embodiment, the plurality of fibers and hydrogel materials are formed using a multilayer coextrusion process step. Additional process steps can be performed to form a tissue engineering scaffold. Such a scaffold can be used to grow biological matter. In one embodiment, stem cells are applied to the scaffold to grow biological material. Process steps can be controlled to determine certain mechanical properties of the resulting biomaterial. In one embodiment, the process steps are controlled to determine the stiffness of the resulting biomaterial. In such an embodiment, the stiffness of the resulting biological material determines physical properties of the biological material grown on the scaffold.

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Wexford, PA, United States of America

Alexander M Jordan