Mc10, Inc.

Epicore Biosystems, Inc.

Alexander J Aranyosi

Jeffrey B Model

Roozbeh Ghaffari

Milan S Raj

Stephen P Lee

Hoi-Cheong Steve Sun

Valerie Susan Hanson

Bryan McGrane

Brian Murphy

Ping-Hung Wei

Cole Papakyrikos

Jessica Wallace

Melissa Seib

Alan P Scarth

Weihua Li

Adam Leech

Ji Hyung Hong

Jeffrey Model

Hoi-Cheung Steve Sun

Bryan Mcgrane

A wearable biofluid volume and composition system includes a microfluidic flexible fluid capture substrate having a microfluidic channel configured as a sweat collection channel and is configured to be worn on a human body and to collect and analyze biofluid. The microfluidic flexible fluid capture substrate further has a plurality of conductive traces and electrodes. An electronic module is attached to the microfluidic flexible fluid capture substrate and is configured to measure and analyze data from the biofluid collected by the microfluidic flexible fluid capture substrate and to transmit the analyzed data to a smart device.

Wearable biofluid volume and composition measurement system

A sweat sensing device includes a flexible body having a first, outwardly facing surface and a second, skin facing surface and a sweat channel formed in the body, the sweat channel having a first end defining a fluid inlet and a second end. A biochemical assay well formed in the sweat channel and an assay material is disposed in the biochemical assay well, the assay material positioned to react with sweat traveling through the sweat channel and to provide one of a visual indicator and an indicator detectable by a camera and connected processor of the flow of the sweat in the sweat channel.

Wearable fluidic system for measuring sweat composition

A sweat collection device includes a flexible body having a first, outwardly facing surface and a second, skin-facing surface, and a sweat collection channel formed in the body, the sweat collection channel having a first end defining a sweat inlet port, and a second end defining a sweat outlet port. The sweat inlet port and the sweat outlet port are configured to be closed and sealed such that the sweat collection device and the collected sweat therein may be stored and shipped.

Wearable fluidic device and system for sweat collection and extraction

An on-body sensor system includes a hub configured to be attached to a surface of a user. The hub being further configured to transmit electrical power and/or data signals into the surface and to receive response data signals from the surface. The system further including at least one sensor node configured to be attached to the surface. The sensor node being further configured to receive the electrical power and data signals from the hub through the surface and to transmit the response data signals into the surface. The electrical power from the hub can power the sensor node and cause or enable the at least one sensor node to generate sensor information that is transmitted back to the hub within the response data signals.

System, devices, and method for on-body data and power transmission

A moisture sensor includes a pair of electrode plates separated by a moisture absorbent material that forms the dielectric of a capacitive sensor. As the absorbent dielectric material absorbs moisture, such as perspiration, the capacitance of the sensor changes reflecting a quantitative measure of perspiration absorbed. The sensor can be stabilized by capacitively coupling the dielectric material to the skin of the user to improve sensor stability and noise rejection. The sensor can include a capacitive sensing integrated circuit that measures the capacitance of the sensor in close proximity to the electrodes to limit the introduction of noise.

Perspiration sensor

The present invention relates to portable devices for point-of-care diagnostics that can perform measurements on a sample (e.g., blood, serum, saliva, or urine) and relay data to an external device for, e.g., data analysis. The device can comprise a paper-based diagnostic substrate and a base substrate that include electronic circuitry and electronic elements necessary for performing the measurements. The device can also comprise an antenna for near field communication with an external device. Another aspect of the invention relates to methods of using these devices.

Quantification of a change in assay

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Medford, MA, United States of America

Alexander J Aranyosi