Genzyme Corporation

Alexander Hee-Hanson

Robert Wilson

Thomas Lever

Michael Parrott

Haiming Wu

Timothy Denyer

Dean Twite

James Bradford

Nicholas Harding

Craig Nelson

Tom Lever

William Vespa

Cedric Delmy

Seth Frankel

According to a first aspect of this disclosure, there is described an injection device includes: a body; a needle shroud retractable into the body including a shroud pin; a collar rotatable with respect to the body and including a cam track engageable with the shroud pin. The cam track includes: a first portion configured to, during retraction of the needle shroud into the body, guide the shroud pin from an initial position to a hold position and cause the collar to rotate relative to the body; a second portion configured to, during extension of the needle shroud from the body subsequent to the retraction, guide the shroud pin from the hold position to a final position and cause the collar to further rotate relative to the body; and a non-return surface configured to, subsequent to the extension, prevent further retraction of the needle shroud into the body.

Collar cam lock for injection devices

A medicament delivery device is described. The medicament delivery device includes a proximal end and a distal end defining a longitudinal axis; a body; and a button arranged at the proximal end and configured to actuate the medicament delivery device. The medicament delivery device further includes a lock ring configured to rotate relative to the body about the longitudinal axis between a first position in which the button is not permitted to move along the longitudinal axis relative to the body, and a second position in which the button is permitted to move along the longitudinal axis relative to the body; a plurality of first indication elements circumferentially spaced around a first portion of the medicament delivery device; and a plurality of second indication elements circumferentially spaced around a second portion of the medicament delivery device.

Medicament delivery device

The application relates to a lock ring for a medicament delivery device. The lock ring comprises a hollow main body formed from a plurality of circumferentially extending portions. Each portion is defined between tool split lines defining circumferential ends of the portions. Each circumferential end of a portion is connected to an adjacent portion along a tool split line. The main body comprises a plurality of bearing elements configured to contact a body of a medicament delivery device. Each of the plurality of bearing elements is configured to form a low friction rotation interface. At least one of the plurality of bearing elements is formed proximate to one of the circumferential ends of a portion of the main body.

Lock ring for a medicament delivery device

A medicament delivery device for injecting medicament which has a body having a proximal end and a distal end, a needle for injecting medicament and an actuation member which is movable relative to the body. The actuation member is movable from a first position to a second position and movable from the second position to a dispensing position for dispensing medicament from the needle. The second position is proximal of the first position. The medicament delivery device further has a cap which is removably attached to the medicament delivery device. The cap has a portion configured to prevent movement of the actuation member from the first position to the second position when the cap is attached to the medicament delivery device.

A medicament delivery device is described. The device includes a body comprising a proximal end and a distal end; a needle for injecting medicament; an actuation member moveable relative to the body for actuating the device; a lock ring configured to rotate relative to the body between a first position in which the actuation member is not permitted to move relative to the body, and a second position in which the actuation member is permitted to move relative to the body; and a cap arrangeable in a capped position in which the cap abuts with and conceals the distal end of the body to conceal the needle; wherein when the cap is in the capped position the lock ring is in a first state in which the lock ring is in the first position and is not permitted to rotate towards the second position; and wherein moving the cap in a distal direction away from the distal end of the body along the longitudinal axis away from the capped position causes the lock ring to be in a second state in which the lock ring is permitted to rotate from the first position towards the second position.

An injection device comprises: an injection device body; a needle shroud comprising a shroud pin; and a collar rotatable with respect to the injection device body and comprising a cam track. During retraction of the needle shroud, a first portion of the cam track guides the shroud pin to a hold position and cause the collar to rotate relative to the injection device body from a first position to a second position. During a subsequent extension of the needle shroud, a second portion of the cam track guides the shroud pin from the hold position to a final position and causes the collar to further rotate relative to the injection device body from the second position to a third position, the second portion comprising a blocking portion configured to prevent extension of the needle shroud from the injection device body when the collar is held in the second position.

Needle shroud latch for injection devices

A damping device for a medicament delivery device, comprising: a generally cylindrical first collar; a housing comprising a generally annular cavity configured to receive at least a portion of the first collar; wherein the first collar is configured to be rotatable relative to the housing about a central longitudinal axis of the damping device, and wherein the cavity is configured to contain a fluid for impeding rotational movement of the first collar relative to the housing; and a sealing arrangement configured to fluidly seal an interface between the housing and the first collar.

Damping device for a medicament delivery device

There is provided a medicament delivery device comprising: a main body arranged to receive a medicament cartridge; a needle for delivery of medicament from the medicament cartridge; a needle cover moveable between an initial position, in which the needle cover covers the needle, and an activated position for dispensing medicament from the medicament delivery device, wherein in the activated position the needle protrudes from a distal end of the needle cover; an outer frame, moveable relative to the main body between an extended position in which the outer frame extends past a distal end of the needle, and a retracted position in which the outer frame is moved towards the main body; an attachment element comprising an adhesive region for attaching the medicament delivery device to a surface when the needle cover is in the activated position, the attachment element comprising a protective barrier covering the adhesive region.

A medicament delivery device has a needle, a body and a needle cover which is axially movable from an initial position to a holding position to a locked position in which the needle cover covers the distal end of the needle. The device has a biasing member configured to bias the needle cover distally, and a guide member configured to rotate relative to the needle cover. One of the guide member and the needle cover has a pin and the other of the guide member and the needle cover has a guide path for guiding the pin. The guide path has a first ramp, a second ramp and a locking abutment surface. When the needle cover is in the locked position then the locking abutment surface is configured to engage the pin to prevent the needle cover from moving proximally away from the locked position.

A medicament delivery device comprises: a needle for injecting a medicament; a body; a needle cover axially movable relative to the body between an extended position and a retracted position; a needle cover biasing member configured to bias the needle cover distally; a medicament delivery mechanism; and a latch movable by the needle cover between an engaged configuration, in which the latch prevents delivery of the medicament, and a disengaged configuration, in which the latch allows delivery of the medicament, wherein the needle cover is configured such that: proximal movement of the needle cover from the extended position towards the retracted position moves the latch from the engaged configuration to the disengaged configuration; and distal movement of the needle cover from the retracted position towards the extended position moves the latch from the disengaged configuration to the engaged configuration.

A medicament delivery device includes: a body; a needle cover axially movable between an extended position and a retracted position; a medicament delivery mechanism including a plunger and a drive member configured to move the plunger to dispense a medicament; an actuation member configured to be actuated relative to the body; and a ratchet mechanism coupled to the medicament delivery mechanism and sequentially movable between a first configuration, second configuration and third configuration, wherein the actuation member and ratchet mechanism are arranged such that: a first actuation of the actuation member moves the ratchet mechanism from the first configuration to the second configuration to cause a first dose of the medicament to be dispensed, and a second actuation of the actuation member, subsequent to the first actuation, moves the ratchet mechanism from the second configuration to the third configuration to cause a second dose of the medicament to be dispensed.

A medicament delivery device comprising a body, a needle, and an actuation member movable proximally from an initial position to a protruded position, and distally from the protruded position to an actuation position. The device has a transfer member which is movable proximally between an extended and a retracted position. In the extended position the distal end of the transfer member protrudes from the body. One of the actuation member and the transfer member has a drive slot and the other of the actuation member and the transfer member comprises a protrusion located in the drive slot. The drive slot has a circumferentially-extending portion having an abutment surface. The protrusion engages the abutment surface to move the actuation member from the initial position to the protruded position.

A medicament delivery device includes a first component, a second component configured to be movable with respect to the first component, and a temperature-dependent interconnect configured to resist movement of the first component relative to the second component. The temperature-dependent interconnect includes an engagement member and a temperature-dependent material configured to engage each other. The temperature-dependent material has a temperature-dependent material characteristic such that the temperature-dependent material has (i) a first material characteristic at a first temperature of the temperature-dependent material to resist movement of the first component with respect to the second component, and (ii) a second material characteristic at a second temperature of the temperature-dependent material to allow movement of the first component with respect to the second component.

A medicament delivery device includes a needle being axially moveable from a retracted position to an exposed position. The device includes an actuation member configured to be movable to an actuation position to cause the needle to move from the retracted position to the exposed position. The device includes a locking member for preventing the movement of the actuation member to the actuation position, and a locking release member being axially moveable towards a proximal end of the medicament delivery device from a first position, in which the locking member is prevented from moving to a release position in which the actuation member is released for the movement of the actuation member to the actuation position, to a second position, in which the locking member is free to move to the release position in which the actuation member is released for the movement of the actuation member to the actuation position.

A medicament delivery device includes an actuator including an actuation member configured to be movable by a user to an actuation position to cause a dose of medicament to be dispensed from the medicament delivery device. The actuator is configured to be movable from a deactivated position in which a user is prevented from moving the actuation member to the actuation position to an activated position in which the actuation member is released for movement by a user to the actuation position. The device includes a temperature-dependent actuator configured to move the actuator from the deactivated position to the activated position in response to a change in temperature of the temperature-dependent actuator.

Growing community of inventors

Melbourn, United Kingdom

Alexander Hee-Hanson