Boehringer Ingelheim International Gmbh

Alexander Bauer

Patrick Garidel

Andreas Langer

Stefan Bassarab

Ingo Michael Presser

Markus Hemminger

Nicole Denkinger

Hans-Joachim Kern

Hans-Hoachim Kern

Double chamber container for holding and combining, e.g., a lyophilizate and a liquid reconstitution medium, comprising

Dual chamber container for lyophilization, process for the filling up and use thereof

A double chamber container for holding and combining a solid lyophilizate and a liquid reconstituting medium, comprising a cylindrical body with a closure at each of the two ends, an upper displaceable closure at the reconstituting medium end, and a lower closure at the lyophilizate end, a separating stopper that can be pushed in the cylindrical body and act as a seal between the upper chamber and the lower chamber, and a bypass arranged underneath the separating stopper, with a length L that is preferably greater than the height H of the separating stopper, wherein at the upper end in the wall of the cylindrical body or in the separating stopper means are provided that allow partial connection of the interior of the cylindrical body to the environment during the lyophilization.

Dual chamber container and process for its filling up

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Biberach, Germany

Alexander Bauer