Emerald Cloud Lab, Inc.

Emerald Therapeutics, Inc.

Alex M Yoshikawa

Daniel J Kleinbaum

Brian M Frezza

George W Fraser

Jonathan K Leung

Bradley M Bond

Courtney E Webster

Shayna L Hilburg

Catherine L Hofler

Ruben E Valas

George N Stanley

Sergio I Villarreal

Robert M Teed

Shivani S Baisiwala

Sean M Fitzgerald

Cameron R Lamoureux

Guillaume Robichaud

Wyatt J Woodson

Srikant Vaithilingam

Asuka Ota

Hayley E Buchman

Yang Choo

Yidan Y Cong

James R McKernan

Ben C Kline

Cheri Y Li

Anand V Sastry

Paul R Zurek

Eric Shyr

Kyla N Velaer

The disclosure provides systems and methods for conducting and managing integrated laboratory experiments. The system includes a variety of laboratory instruments that are connected to conduct a large number of different types of experiments, and an interface for a user to design experiments and adjust parameters for the experiments. Given the integration, the system can further take data from related samples and instruments for determining or adjusting certain experimental parameters for optimized experimental efficiency and results.

System and method for management, execution, and analysis of laboratory experiments

The disclosure provides systems and methods for data analysis of experimental data. The analysis can include reference data that are not directly generated from the present experiment, which reference data may be values of the experimental parameters that were either provided by a user, computed by the system with input from a user, or computed by the system without using any input from a user. Another example of such reference data may be information about the instrument, such as the calibration method of the instrument.

Laboratory experiment data exploration and visualization

A fabrication process for producing, annealing, and conjugating nucleic acid molecules is implemented, under the direction of one or more computer programs, on two or more instruments, for carrying out the process. The process can include: (a) synthesizing, on a solid support and in a plurality of reactions, at least one of a nucleic acid and a peptide nucleic acid, and cleaving the synthesized biomolecule product from the support, providing a sample of synthesized biomolecule product from each reaction of the plurality; (b) measuring, for each sample, the volume of the sample and/or the concentration of the product; (c) subjecting the product from each reaction to chromatography under conditions suitable for achieving single-base-resolution for the product, the conditions being a function of the volume and/or concentration measured in (b); and then (d) collecting and pooling, from the chromatography of (c) for each sample, peaks that correspond to the product.

Systems and methods for automated preparation of nucleic acids

Growing community of inventors

South San Francisco, CA, United States of America

Alex M Yoshikawa