Zoll Circulation, Incorporated

Xoft, Inc.

Cardima, Inc.

Xoft Microtube, Inc.

Alex L Lim

Venkata Vishnu Gurukula

Richard A Helkowski

Jeremy Thomas Dabrowiak

Paul A Lovoi

Daren Stewart

Thomas W Rusch

Masouneh Mafi

Masoumeh Mafi

Darius Francescatti

Peter Clark Smith

Heike Hausen

Richard E Hill

James Mazzone

Eric K Y Chan

Tim Ngoc Huynh

John Rieke

Dung A Nguyen

Daren L Stewart

Jack I Irwin

A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.

Patient temperature control catheter with helical heat exchange paths

An intravascular heat exchange catheter has serpentine-like supply and return conduits circulating working fluid with a heat exchange system to warm or cool a patient in which the catheter is intubated.

Intravascular heat exchange catheter with rib cage-like coolant path

Disclosure includes fluid-circulating heat exchange catheters, systems and related methods useable for controlling a patient's body temperature.

Fluid-circulating catheters useable for endovascular heat exchange

A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.

Transatrial patient temperature control catheter

A catheter has a hollow conduit through which working fluid from a heat exchange system flows. The conduit in turn is configured to extend along a longitudinal central axis in a continuously varying non-constant azimuthal orientation so that it defines a non-round enclosed passageway through which blood can flow to exchange heat through a wall of the conduit with the working fluid flowing within the conduit.

Intravascular heat exchange catheter with non-round coiled coolant path

A patient temperature control catheter () includes working fluid supply () and return () lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils () axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel. Alternate centering structures () are disclosed.

Self-centering patient temperature control catheter

A patient temperature control catheter includes working fluid supply and return lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel.

A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance.

Patient temperature control catheter with outer sleeve cooled by inner sleeve

A catheter has a series of hollow loops arranged along a tube for carrying working fluid from a heat exchange system to exchange heat with a patient in whom the catheter is advanced. The loops when inflated are transverse to the catheter axis and parallel to each other, and circumscribe a hollow passageway through which blood can flow. Blood also flows around the outer perimeters of the loops.

Intravascular heat exchange catheter with multiple spaced apart discrete coolant loops

An apparatus for exchanging heat in a patient has a first elongated heat exchange catheter carrying circulating working fluid to and from a heat exchange system and a second elongated heat exchange catheter carrying circulating working fluid to and from the heat exchange system. The apparatus has a connector supporting proximal portions of both catheters while distal portions of the catheters are disposed inside a patient's vasculature to exchange heat with the patient.

System and method for doubled use of patient temperature control catheter

A vaginal brachytherapy applicator is versatile to different anatomies and more comfortable to the patient than prior applicators. An inflatable balloon on a shaft may be inelastic or elastic. In one embodiment the shaft is rotatable relative to the balloon for enabling a ring or band of dose delivery, for versatility in radiation placement. Alternatively, the source can be rotated and pulled back within a stationary shaft. An adjustment is provided for reducing the length of balloon that inflates, to accommodate different anatomies and positions. Although isotope radiation sources can be used in the applicator, an electronic source is preferred, and the system and method include procedures for using the applicator with an electronic source.

Growing community of inventors

Santa Clara, CA, United States of America

Alex L Lim