Hoffmann-la Roche Inc.

F. Hoffmann-la Roche Ag

Alex Kohn

Angelika Fuchs

Otto Huber

Eckhart Guthoehrlein

Franziska Mech

Jan Kuentzer

An image analysis method for analyzing an IHC tissue sample includes storing, for each of one or more sets of digital images, a set-ID in a spatial database of a spatial DBMS, the images of each set depicting the same or adjacent layers of the IHC tissue sample; storing, for each of the, a plurality of spatial data objects in the database in association with the set-ID; creating, by the spatial DBMS, at least one spatial index covering the objects of the images contained in the one or more sets; applying, by the spatial DBMS, a spatial database operation on the at least one spatial index for determining the relative positions of objects of two or more images of a selected set; and providing the relative positions as input for determining the distance and/or relative position of the biomedical features of the tissue sample.

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Penzberg, Germany

Alex Kohn