Somalogic, Incorporated

Alex A E Stewart

Rachel M Ostroff

Malti P Nikrad

Stephen Alaric Williams

Stuart G Field

Rosalynn Dianne Gill

Larry M Gold

Dominic Zichi

Michael Riel-Mehan

Edward N Brody

Marty Stanton

The present application includes biomarkers, methods, devices, reagents, systems, and kits for the detection and diagnosis of lung cancer. In one aspect, the application provides biomarkers that can be used alone or in various combinations to diagnose lung cancer or permit the differential diagnosis of pulmonary nodules as benign or malignant. In another aspect, methods are provided for diagnosing lung cancer in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Table 1, Col. 2, wherein the individual is classified as having lung cancer, or the likelihood of the individual having lung cancer is determined, based on the at least one biomarker value.

Lung cancer biomarkers and uses thereof

Methods, compositions, and kits for predicting whether a subject with chronic obstructive pulmonary disease (COPD) or at risk of developing COPD is likely to have progressive COPD are provided. Methods, compositions, and kits for predicting whether lung function is likely to decline in a subject with COPD or at risk for developing COPD are also provided.

Chronic obstructive pulmonary disease (COPD) biomarkers and uses thereof

Growing community of inventors

Waltham, MA, United States of America

Alex A E Stewart