Università Degli Studi Di Roma "La Sapienza"

Tes Teleinformatica E Sistemi S.r.l.

Alessandro Rosa

Pasquale Russo

Irene Bozzoni

Annamria D'Ippolito

Michela Alessandra Denti

Alessandro Fatica

The authors describe an expression system for the correct, stable and effective expression in mammalian cells of a siRNA comprising: a) a polymerase II RNA-dependent promoter derived from the U1 RNA gene; downstream from the sequence b) suitable restriction sites for the cloning of the sequence transcribing the pre-siRNA; downstream from these sites c) sequences derived from the sequences at 3' of the gene for U1 snRNA that are necessary and sufficient for the correct formation of 3&#x2032; of the presiRNA.

siRNA expression system

A transceiver or transponder particularly for synthetic aperture radar, or SAR, systems, operating in a frequency band having a central frequency, the transponder comprising a receiver () and a transmitter () both thermally stable and made by microstrip technology, the receiver () and the transmitter () being adapted to receive and to transmit, respectively, an electromagnetic wave provided with at least one linear polarisation, the receiver () being connected to the transmitter () by amplifier means comprising an amplifier unit () for each linear polarisation of the wave received by the receiver (), each amplifier unit () including at least two amplifier stages () cascade arranged along a single microstrip and interconnected to one another and to an input and to an output of the corresponding amplifier unit () by means of coupling or matching stages (), the output signal of each amplifier unit () having substantially the same frequency as the input signal thereto, the amplifier units () having substantially the same gain, the gain being no lower than 25 dB, the transponder being phase stable so that each linear polarisation of the transmitted electromagnetic wave has phase variations in time no higher than 20&#xb0;, the transponder further comprising electromagnetic decoupling means () between the transmitter () and the receiver ().

Transponder having high phase stability, particularly for synthetic aperture radar, or sar, systems

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Rome, Italy

Alessandro Rosa