Becton Dickinson and Company Limited

Springleaf Therapeutics, Inc.

Alessandro Egidio Pizzochero

J Richard Gyory

Charles George Hwang

John Prudden

Christopher Kovalchick

Russell S Cole

Joseph Iskandar

Justin David Cumming

Kurt Maw

Justin Fisk

Christopher Petroff

Kenneth Focht

Matthew J Perry

Andrew Allegretti

Jeffrey Reed

Ajit D'Souza

Joseph M Gordon

Leya Colavito

Gail Marie Siewiorek

Nir Swenson

Joseph Biehler

Mark Wood

Dana Michael Cote

Yi Su

Eric Hassenpflug

Glenn R Booma

Muzaffer Yalgin Ozsecen

Timothy Blum

Cory Baker

Jeffrey Held

Joeseph Gordon

Owen Ryan

Rekha Doshi

John Adams

Shane Kilcolm

Richard J Gyory

A fluid delivery device has a syringe barrel-type reservoir with plunger and plunger driver assembly comprising nested, telescopic screws comprising an innermost screw keyed to a first side of the plunger or intermediate pusher to prevent rotation. In a fully retracted position, the nested screws do not extend into the reservoir. The nested screws all have right handed threads and employ the same pitch in their respective inner thread and outer thread designs. The outermost screw is connected to a motor for controllable rotation. The decreasing torque ratios from the outermost to innermost screw member and anti-rotation feature allows the innermost screw to advance the plunger into the reservoir before the adjacent concentric screw member commences rotating and advancing within its corresponding screw, and so on, to translate the plunger and expel fluid in a fluid chamber defined on the other, second side of the plunger.

Multiple telescoping screw-driven pump mechanism with anti-rotation of innermost screw keyed to reservoir plunger in fluid delivery device

A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system.

Rotational metering pump for medication patch

A system and method is provided for detecting fluid low-volume and occlusion in a device using force sensing resistor (FSR) sensor. One or more force sensing resistors are positioned in communication with a fluid channel at one or more of a pump intake and pump outlet to detect pressure in the fluid channel. The pressure is detected through communication with the force sensing resistor and indicates an irregular system condition including but not limited to, fluid low-volume level and occlusion. Also provided are a fluid flow sensor (e.g., FSR or MEMS sensor) disposed relative to an embedded fluid channel in the base of a wearable medicine delivery pump.

Force sensing resistor for liquid low-volume detection and occlusion sensing and methods and apparatuses for flow sensing along fluid path in fluid delivery device

A medicament delivery device comprising a housing connected to a base and enclosing an interior, the interior having a fluid channel wherein the fluid channel passes from a first position in the interior, to a second position outside the interior, and to a third position in the interior.

Plate with integral fluid path channels

A fluid delivery device has a syringe barrel-type reservoir with plunger, and plunger driver assembly comprising double-acting, telescoping lead screws that is located behind and outside of the barrel. Simultaneously and counter-rotating sleeve screw and center screw telescope out of a nested configuration of the plunger driver assembly and into the reservoir at a rate of double their individual and equal pitch and lead parameters when the sleeve screw is rotated. A threaded nut and gear anchor disposed on an end of the barrel receive the sleeve screw and the threaded nut causes the sleeve screw to translate and rotate in response to motor operation. A distal end of the center screw can be keyed to a plunger pusher for anti-rotation constraint when the motor is imparting rotation on the threaded nut and sleeve screw.

Double-acting, telescoping screw-driven pump mechanism disposed externally to reservoir in fluid delivery device

Rotational metering pump for insulin patch

A rotary pump for a fluid metering system is provided. The rotary pump reciprocates, and is reversed by a signal from a limit switch that is deflected by an actuator arm on a rotating sleeve of the pump system. The rotary pump includes a plunger and optional stopper formed from a two-shot molding process, and including seals overmolded onto the head of the plunger and the head of the optional stopper.

A low medicament sensor for a medicament delivery device having a reservoir, a pump, and a fluid path therebetween for medicament, the sensor including a switch and a snap dome. The snap dome is initially in contact with the switch, in fluid communication with the fluid path, and configured to snap out of contact with the switch when a pressure within the snap dome decreases below a predetermined pressure.

Liquid medicament reservoir empty detection sensor and occlusion sensor for medicament delivery device

A filling member () in a medicament delivery device (), the filling member () includes a first conduit () that fluidly communicates with a reservoir () and a second conduit () that fluidly communicates with a pump () and with the first conduit (), wherein the filling member () provides two-way medicament flow that enters the reservoir () via the first conduit (), exits the reservoir () into the first conduit () and the second conduit (), and exits the second conduit () to the pump (). The reservoir () includes a reservoir tube (A) having one end that is formed with the reservoir (), and the reservoir tube (A) having another end that is press fit to the filling member () to establish fluid communication with the reservoir ().

Fluid interconnection scheme between reservoir, pump and filling member

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Chelmsford, MA, United States of America

Alessandro Egidio Pizzochero