Immatics Us, Inc.

Aleksandra Norwicka

Norbert Hilf

Sabrina Kuttruff-Coqui

Steffen Walter

Melinda Mata

Yannick Bulliard

Monique Dao

Sarah Missell

The present disclosure relates to expansion and activation of T cells. In an aspect, the present disclosure relates to expansion and activation of γδ T cells that may be used for transgene expression. In another aspect, the disclosure relates to expansion and activation of γδ T cells while depleting α- and/or β-TCR positive cells. T cell populations comprising expanded γδ T cell and depleted or reduced α- and/or β-TCR positive cells are also provided for by the instant disclosure. The disclosure further provides for methods of using the disclosed T cell populations.

Methods for expanding and activating γσ T cells for the treatment of cancer and related malignancies

Growing community of inventors

Nowicka, TX, United States of America

Aleksandra Norwicka