Musculoskeletal Transplant Foundation

The Methodist Hospital

Other

The Methodist Hospital System

Aldona Jedrysiak Spiegel

Kai-Roy Wang

Michael Locarno

Gregory P Adams

Todd J Nilsen

Evangelia Chnari

Robert S Troxclair

Antonio M Bunce

Disclosed herein are hydrogel devices and methods of making an use thereof. The devices can comprise: a continuous hydrogel matrix; a first chamber in the hydrogel matrix; and a second chamber in the hydrogel matrix; wherein the first chamber and the second chamber are each independently perfusable; wherein the first chamber is fluidly independent from the second chamber; wherein the first chamber is configured to be at least partially filled with adipose tissue; wherein the second chamber is configured to be at least partially filled with an oxygenated fluid; wherein the first chamber is defined by a first border; wherein the second chamber is defined by a second border; and wherein the first chamber and the second chamber are spaced apart from each other by an average distance of from 50 micrometers (microns, &#x3bc;m) to 800 &#x3bc;m as measured from the first border to the second border.

Hydrogel devices and methods of making and use thereof

Soft tissue repair grafts are provided for supporting, covering, and/or retaining an implant positioned in the body of a subject. The grafts are particularly suitable for use for pre-pectoral breast reconstruction with a breast implant or tissue expander. The grafts include positional notches for more accurate positioning in a subject. The grafts also include at least one cuff element which is folded to form a reinforced folded edge for suturing the graft more securely to adjacent tissues than previously known grafts. The grafts also include a plurality of arcuate slots which form a plurality of circular patterns arranged concentrically about a focal point, thereby enabling the grafts to expand without tearing and to conform more closely to the implant and/or adjacent body tissues such as the breast pocket, than previously known grafts. Acellular dermal matrices are particularly suitable for making the soft tissue repair grafts.

Soft tissue repair grafts and processes for preparing and using same

A dermal tissue allograft includes a dermal matrix having a profile including first and second vertices, a first imaginary axis extending between the first and second vertices, a first peripheral edge extending along a continuous path from the first vertex to the second vertex on a first side of the first imaginary axis, and a second peripheral edge extending along a continuous path from the first vertex to the second vertex on a second side of the first imaginary axis. The first peripheral edge includes an apogee, a convex portion, and a concave portion. The convex and concave portions meet at a transition point located on the first peripheral edge between its apogee and the second vertex. The second peripheral edge includes an apogee and is convex. The second perpendicular distance is greater than the first perpendicular distance. The dermal matrix has a substantially uniform thickness across its profile.

Asymmetric tissue graft

Soft tissue repair graft

A tube flushing device has a shell having a first housing and a second housing connected on a side thereof so as to be movable between an open position and a closed position. A first pair of wheels are rotatably mounted in the first housing. A second pair of wheels rotatably mounted in the second housing. The first pair of wheels engages the second pair of wheels when the housings are in the closed position. The shell has openings on opposite ends thereof. A tube can extend through the openings and between the first and second pair of wheels so as to allow fluids therein to be flushed therefrom as the shell moves along the length of the tube.

Apparatus for flushing fluids from a tube

Growing community of inventors

Houston, TX, United States of America

Aldona Jedrysiak Spiegel